Stem-loop aae-mir-2a

Accession

MI0013443

Description

Aedes aegypti aae-mir-2a precursor miRNA

Gene family

MIPF0000049; mir-2

Literature search

4 open access papers mention aae-mir-2a
(27 sentences)

Sequence

36940 reads, 1891 reads per million, 2 experiments

ugggaacuguuuccACUCUCAAAGUGGUUGUGAAAugaguuacucuugaacgaucucaUAUCACAGCCAGCUUUGAAGAGCgaaacgguuucucgca
.((((((((((((..((((((((((((((((((.(((((...............))))).))))))))).))))).)))).))))))))))))....

Structure

---u            cA    -     -         A     uuacuc 
    gggaacuguuuc  CUCU CAAAG UGGUUGUGA Augag      u
    ||||||||||||  |||| ||||| ||||||||| |||||      u
    ucuuuggcaaag  GAGA GUUUC ACCGACACU Uacuc      g
acgc            -C    A     G         A     uagcaa 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

supercont1.268: 888581-888677 [-]

Clustered miRNAs

4 other miRNAs are < 10 kb from aae-mir-2a

Mature aae-miR-2a-5p

• Accession: MIMAT0014225
• Description: Aedes aegypti aae-miR-2a-5p mature miRNA
• Sequence: 15 - ACUCUCAAAGUGGUUGUGAAA - 35
• Evidence: experimental ; Illumina [2]

Mature aae-miR-2a-3p

• Accession: MIMAT0014226
• Description: Aedes aegypti aae-miR-2a-3p mature miRNA
• Sequence: 59 - UAUCACAGCCAGCUUUGAAGAGC - 81
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119