miRBase entry: aae-mir-278

Stem-loop aae-mir-278


Accession
MI0013450
Description
Aedes aegypti aae-mir-278 precursor miRNA
Gene family
MIPF0000155; mir-278

Literature search
2 open access papers mention aae-mir-278
(4 sentences)

Sequence

2442 reads, 124 reads per million, 2 experiments
uggugcgaACGGACGAUAGUCUUCAGCGGCCgugcauuugauagaauuggUCGGUGGGACUUUCGUCCGUUUguaaccgcc
.(((((((((((((((.(((((.((.((((((...((((....)))))))))).))))))).)))))))))))).)))...

Structure
--u   -            U     U  G      ugc    g 
   ggu gcgaACGGACGA AGUCU CA CGGCCg   auuu a
   ||| |||||||||||| ||||| || ||||||   ||||  
   cca ugUUUGCCUGCU UCAGG GU GCUggu   uaag u
ccg   a            U     -  G      ---    a 


Annotation confidence High
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Comments
This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context
supercont1.16: 3596261-3596341 [+]

Database links

Mature aae-miR-278-5p

Accession MIMAT0014237
Description Aedes aegypti aae-miR-278-5p mature miRNA
Sequence 9 - ACGGACGAUAGUCUUCAGCGGCC - 31
Evidence experimental
454 [1], Illumina [2]

Mature aae-miR-278-3p

Accession MIMAT0014238
Description Aedes aegypti aae-miR-278-3p mature miRNA
Sequence 51 - UCGGUGGGACUUUCGUCCGUUU - 72
Evidence experimental
Illumina [2]

References

  1. PubMed ID: 19961592
    Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
    Li S, Mead EA, Liang S, Tu Z
    BMC Genomics (2009) 10:581

  2. PubMed ID: 20167119
    Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
    Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
    BMC Genomics (2010) 11:119