Stem-loop hsa-mir-219b

Accession

MI0017299

Symbol

HGNC: MIR219B

Description

Homo sapiens hsa-mir-219b precursor miRNA mir-219

Gene
family

RF00251; mir-219

Literature search

70 open access papers mention hsa-mir-219b
(245 sentences)

Sequence

149932 reads, 21 reads per million, 66 experiments

ggagcucagccacAGAUGUCCAGCCACAAUUCUCGguuggccgcagacucguacaAGAAUUGCGUUUGGACAAUCAGUggcgaagccc
((.(((..(((((.(((((((((.(.((((((((((((.......))).))....))))))).).)))))).))).)))))..)))))

Structure

  a   ca     A   -      C A       ----  -   gg 
gg gcu  gccac GAU GUCCAG C CAAUUCU    CG guu  c
|| |||  ||||| ||| |||||| | |||||||    || |||  c
cc cga  cggUG CUA CAGGUU G GUUAAGA    gc cag  g
  -   ag     A   A      U C       acau  u   ac 

Annotation confidence High

Genome context

chr9: 128392621-128392708 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-219b

Mature hsa-miR-219b-5p

• Accession: MIMAT0019747
• Description: Homo sapiens hsa-miR-219b-5p mature miRNA
• Sequence: 14 - AGAUGUCCAGCCACAAUUCUCG - 35
• Evidence: experimental ; Illumina [1]

Mature hsa-miR-219b-3p

• Accession: MIMAT0019748
• Description: Homo sapiens hsa-miR-219b-3p mature miRNA
• Sequence: 56 - AGAAUUGCGUUUGGACAAUCAGU - 78
• Evidence: experimental ; Illumina [1]

References

1. PubMed ID: 21199797
   Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene
   "Persson H, Kvist A, Rego N, Staaf J, Vallon-Christersson J, Luts L, Loman N, Jonsson G, Naya H, Hoglund M, Borg A, Rovira C"
   "Cancer Res (2011) 71:78-86


2. PubMed ID: 21911355
   miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades
   "Friedlander MR, Mackowiak SD, Li N, Chen W, Rajewsky N"
   "Nucleic Acids Res (2012) 40:37-52