Stem-loop cel-mir-41

Accession

MI0000012

Description

Caenorhabditis elegans cel-mir-41 precursor miRNA

Literature search

7 open access papers mention cel-mir-41
(14 sentences)

Sequence

8781 reads, 310 reads per million, 16 experiments

gggucccagagaccuuGGUGGUUUUUCUCUGCAGUGAUAgauacuucuaacaacucgcuaUCACCGGGUGAAAAAUCACCUAggucuggagccuccu
((.(((...((((((.(((((((((((((((..(((((((.................))))))))))).))))))))))).))))))))).))....

Structure

----  g   cag      u           -    CA       auacuuc 
    gg ucc   agaccu GGUGGUUUUUC UCUG  GUGAUAg       u
    || |||   |||||| ||||||||||| ||||  |||||||       a
    cc agg   ucuggA CCACUAAAAAG GGGC  CACUauc       a
uccu  g   ---      U           U    --       gcucaac 

Annotation confidence Medium

Genome context

chrII: 11538308-11538404 [+]

Clustered miRNAs

6 other miRNAs are < 10 kb from cel-mir-41

Mature cel-miR-41-3p

• Accession: MIMAT0000012
• Description: Caenorhabditis elegans cel-miR-41-3p mature miRNA
• Sequence: 61 - UCACCGGGUGAAAAAUCACCUA - 82
• Evidence: experimental ; cloned [1-2], 454 [3], Illumina [4,6], CLIPseq [5]

Mature cel-miR-41-5p

• Accession: MIMAT0020770
• Description: Caenorhabditis elegans cel-miR-41-5p mature miRNA
• Sequence: 17 - GGUGGUUUUUCUCUGCAGUGAUA - 39
• Evidence: experimental ; Illumina [6]

References

1. PubMed ID: 11679671
   An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
   "Lau NC, Lim LP, Weinstein EG, Bartel DP"
   "Science (2001) 294:858-862


2. PubMed ID: 12672692
   The microRNAs of Caenorhabditis elegans
   "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
   "Genes Dev (2003) 17:991-1008


3. PubMed ID: 17174894
   Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
   "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
   "Cell (2006) 127:1193-1207


4. PubMed ID: 19460142
   Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
   Kato M, de Lencastre A, Pincus Z, Slack FJ
   Genome Biol (2009) 10:R54


5. PubMed ID: 20062054
   Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
   "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
   "Nat Struct Mol Biol (2010) 17:173-179


6. PubMed ID: 21307183
   Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer
   "Warf MB, Johnson WE, Bass BL"
   "RNA (2011) 17:563-577