miRBase entry: cel-mir-43

Stem-loop cel-mir-43


Accession
MI0000014
Description
Caenorhabditis elegans cel-mir-43 precursor miRNA mir-43
Gene
family?
RF00795; mir-43

Literature search
2 open access papers mention cel-mir-43
(4 sentences)

Sequence

4596 reads, 113 reads per million, 14 experiments
uauuggcacuagucgcccguGACAUCAAGAAACUAGUGAUUAUGccaaaccacagggacaUAUCACAGUUUACUUGCUGUCGCgggcggugcugaguu
..(((((((....(((((((((((.(((((((((.(((((.(((((.........)).))))))))))))).)))).))))))))))))))))))...

Structure
-ua       uagu           U    -     A     U   -  aaa 
   uuggcac    cgcccguGACA CAAG AAACU GUGAU AUG cc   c
   |||||||    ||||||||||| |||| ||||| ||||| ||| ||   c
   agucgug    gcgggCGCUGU GUUC UUUGA CACUA Uac gg   a
uug       ----           C    A     -     -   a  gac 


Annotation confidence High
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Genome context
chrII: 11889910-11890007 [+]
Clustered miRNAs
3 other miRNAs are < 10 kb from cel-mir-43
Name Accession Chromosome Start End Strand Confidence




Database links

Mature cel-miR-43-3p

Accession MIMAT0000014
Description Caenorhabditis elegans cel-miR-43-3p mature miRNA
Sequence 61 - UAUCACAGUUUACUUGCUGUCGC - 83
Evidence experimental
cloned [1-4], Northern [1], 454 [5], Illumina [6-7]
Database links
Predicted targets

Mature cel-miR-43-5p

Accession MIMAT0020308
Description Caenorhabditis elegans cel-miR-43-5p mature miRNA
Sequence 21 - GACAUCAAGAAACUAGUGAUUAUG - 44
Evidence experimental
Illumina [7]
Database links

References

  1. PubMed ID: 11679671
    An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    "Lau NC, Lim LP, Weinstein EG, Bartel DP"
    "Science (2001) 294:858-862

  2. PubMed ID: 12672692
    The microRNAs of Caenorhabditis elegans
    "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
    "Genes Dev (2003) 17:991-1008

  3. PubMed ID: 12747828
    MicroRNAs and other tiny endogenous RNAs in C. elegans
    "Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D"
    "Curr Biol (2003) 13:807-818

  4. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  5. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  6. PubMed ID: 11679672
    An extensive class of small RNAs in Caenorhabditis elegans
    "Lee RC, Ambros V"
    "Science (2001) 294:862-864

  7. PubMed ID: 21307183
    Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer
    "Warf MB, Johnson WE, Bass BL"
    "RNA (2011) 17:563-577