miRBase entry: cel-mir-58a

Stem-loop cel-mir-58a


Accession
MI0000029
Description
Caenorhabditis elegans cel-mir-58a precursor miRNA mir-58
Gene
family?
RF00835; mir-58

Literature search
19 open access papers mention cel-mir-58a
(216 sentences)

Sequence

49432276 reads, 269408 reads per million, 16 experiments
gcucgucauauccauUGCCCUACUCUUCGCAUCUCAUCacuucguccaauaccauagggaUGAGAUCGUUCAGUACGGCAAUggacugagcuagagu
(((((.....(((((((((.((((...((.((((((((.(((.((.....))...)))))))))))))...)))).))))))))).)))))......

Structure
------     ucaua         C    CUU  C        a   --c  c 
      gcucg     uccauUGCC UACU   CG AUCUCAUC cuu   gu c
      |||||     ||||||||| ||||   || |||||||| |||   || a
      cgagu     aggUAACGG AUGA   GC UAGAGUag gga   ca a
ugagau     ----c         C    CUU  -        -   uac  u 


Annotation confidence High
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Genome context
chrIV: 3233254-3233350 [+]

Database links

Mature cel-miR-58a-5p

Accession MIMAT0015100
Description Caenorhabditis elegans cel-miR-58a-5p mature miRNA
Sequence 16 - UGCCCUACUCUUCGCAUCUCAUC - 38
Evidence experimental
CLIPseq [7]
Database links

Mature cel-miR-58a-3p

Accession MIMAT0000030
Description Caenorhabditis elegans cel-miR-58a-3p mature miRNA
Sequence 61 - UGAGAUCGUUCAGUACGGCAAU - 82
Evidence experimental
cloned [1-4], 454 [5], Illumina [6], CLIPseq [7]
Database links
Predicted targets

References

  1. PubMed ID: 11679671
    An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    "Lau NC, Lim LP, Weinstein EG, Bartel DP"
    "Science (2001) 294:858-862

  2. PubMed ID: 12672692
    The microRNAs of Caenorhabditis elegans
    "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
    "Genes Dev (2003) 17:991-1008

  3. PubMed ID: 12747828
    MicroRNAs and other tiny endogenous RNAs in C. elegans
    "Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D"
    "Curr Biol (2003) 13:807-818

  4. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  5. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  6. PubMed ID: 20062054
    Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
    "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
    "Nat Struct Mol Biol (2010) 17:173-179

  7. PubMed ID: 11679672
    An extensive class of small RNAs in Caenorhabditis elegans
    "Lee RC, Ambros V"
    "Science (2001) 294:862-864