Stem-loop cel-mir-66

Accession

MI0000037

Description

Caenorhabditis elegans cel-mir-66 precursor miRNA

Literature search

3 open access papers mention cel-mir-66
(6 sentences)

Sequence

781718 reads, 7173 reads per million, 16 experiments

ccacaaaaaugccauaCAUGACACUGAUUAGGGAUGUGAugaauguuaagaucccgaucAAAUUCCUAACGGUGUCAAACauggcguaugugguuguag
(((((...(((((((...((((((((.((((((((.((((................)))).))))))))))))))))...))))))).)))))......

Structure

------     aaa       aCA        A        G    gaauguu 
      ccaca   augccau   UGACACUG UUAGGGAU UGAu       a
      |||||   |||||||   |||||||| |||||||| ||||        
      ggugu   ugcggua   ACUGUGGC AAUCCUUA Acua       a
gauguu     --a       CAA        -        A    gcccuag 

Annotation confidence Medium

Genome context

chrIII: 2173108-2173206 [+]

Clustered miRNAs

3 other miRNAs are < 10 kb from cel-mir-66

Mature cel-miR-66-5p

• Accession: MIMAT0000038
• Description: Caenorhabditis elegans cel-miR-66-5p mature miRNA
• Sequence: 17 - CAUGACACUGAUUAGGGAUGUGA - 39
• Evidence: experimental ; cloned [1-2], Northern [1], 454 [3], Illumina [4-5]

Mature cel-miR-66-3p

• Accession: MIMAT0020315
• Description: Caenorhabditis elegans cel-miR-66-3p mature miRNA
• Sequence: 60 - AAAUUCCUAACGGUGUCAAAC - 80
• Evidence: experimental ; Illumina [5]

References

1. PubMed ID: 11679671
   An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
   "Lau NC, Lim LP, Weinstein EG, Bartel DP"
   "Science (2001) 294:858-862


2. PubMed ID: 12672692
   The microRNAs of Caenorhabditis elegans
   "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
   "Genes Dev (2003) 17:991-1008


3. PubMed ID: 17174894
   Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
   "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
   "Cell (2006) 127:1193-1207


4. PubMed ID: 19460142
   Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
   Kato M, de Lencastre A, Pincus Z, Slack FJ
   Genome Biol (2009) 10:R54


5. PubMed ID: 21307183
   Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer
   "Warf MB, Johnson WE, Bass BL"
   "RNA (2011) 17:563-577