Accession
MI0000118
Description
Drosophila melanogaster
dme-mir-2a-2 precursor miRNA
Literature search
32 open access papers mention dme-mir-2a-2
(194 sentences)
(194 sentences)
Sequence
678575
reads,
16640
reads per million, 49 experiments
aucuaagCCUCAUCAAGUGGUUGUGAUAuggauacccaacgcaUAUCACAGCCAGCUUUGAUGAGCuaggau
((((.(((.(((((((((((((((((((((...........)))))))))))))..))))))))))).))))
((((.(((.(((((((((((((((((((((...........)))))))))))))..))))))))))).))))
Structure
a C -- gaua
aucu agC UCAUCAAG UGGUUGUGAUAug c
|||| ||| |||||||| ||||||||||||| c
uagg uCG AGUAGUUU ACCGACACUAUac c
a - CG gcaa
Annotation confidence
High
Do you think this miRNA is real?
Comments
Stark et al. [2] have identified targets for miR-2 in Drosophila using computational prediction followed by experimental validation. miR-2 regulates the proapoptotic genes reaper, grim and sickle, suggesting that it may be involved in the control of apoptosis.
Genome context
chr2L: 19569490-19569561 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from dme-mir-2a-2
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Database links
Mature dme-miR-2a-3p
| Accession | MIMAT0000106 |
| Description | Drosophila melanogaster dme-miR-2a-3p mature miRNA |
| Sequence | 44 - UAUCACAGCCAGCUUUGAUGAGC - 66 |
| Evidence |
experimental
cloned [1,4], Northern [1,3], 454 [5-6], Illumina [6] |
| Database links |
|
Mature dme-miR-2a-2-5p
| Accession | MIMAT0020781 |
| Description | Drosophila melanogaster dme-miR-2a-2-5p mature miRNA |
| Sequence | 8 - CCUCAUCAAGUGGUUGUGAUA - 28 |
| Evidence | not_experimental |
| Database links |
|
References
|
