miRBase entry: dme-mir-12

Stem-loop dme-mir-12


Accession
MI0000132
Description
Drosophila melanogaster dme-mir-12 precursor miRNA mir-12
Gene
family?
RF00751; mir-12

Literature search
11 open access papers mention dme-mir-12
(35 sentences)

Sequence

2100670 reads, 16374 reads per million, 49 experiments
uacgguUGAGUAUUACAUCAGGUACUGGUgugccuuaaauccaacaacCAGUACUUAUGUCAUACUACGCcgug
((((((..(((((.((((.((((((((((((............)).)))))))))))))).)))))..))))))

Structure
      UG     U    C          -  gccuu 
uacggu  AGUAU ACAU AGGUACUGGU gu     a
||||||  ||||| |||| |||||||||| ||      
gugcCG  UCAUA UGUA UUCAUGACca ca     a
      CA     C    -          a  accua 


Annotation confidence High
Do you think this miRNA is real?

Genome context
chrX: 15509473-15509546 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from dme-mir-12
Name Accession Chromosome Start End Strand Confidence




Database links

Mature dme-miR-12-5p

Accession MIMAT0000117
Description Drosophila melanogaster dme-miR-12-5p mature miRNA
Sequence 7 - UGAGUAUUACAUCAGGUACUGGU - 29
Evidence experimental
cloned [1,3], Northern [1-2], 454 [4-5], Illumina [5]
Database links

Mature dme-miR-12-3p

Accession MIMAT0020794
Description Drosophila melanogaster dme-miR-12-3p mature miRNA
Sequence 49 - CAGUACUUAUGUCAUACUACGC - 70
Evidence not_experimental
Database links

References

  1. PubMed ID: 11679670
    Identification of novel genes coding for small expressed RNAs
    "Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T"
    "Science (2001) 294:853-858

  2. PubMed ID: 12812784
    Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity
    "Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V"
    "Dev Biol (2003) 259:9-18

  3. PubMed ID: 12919683
    The small RNA profile during Drosophila melanogaster development
    "Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T"
    "Dev Cell (2003) 5:337-350

  4. PubMed ID: 17989254
    Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    "Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC"
    "Genome Res (2007) 17:1850-1864

  5. PubMed ID: 17989255
    Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
    "Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M"
    "Genome Res (2007) 17:1865-1879