Accession
MI0000269
Symbol
HGNC:
MIR181A2
Description
Homo sapiens
hsa-mir-181a-2 precursor miRNA
Literature search
487 open access papers mention hsa-mir-181a-2
(2580 sentences)
(2580 sentences)
Sequence
2189914
reads,
3157
reads per million, 140 experiments
agaagggcuaucaggccagccuucagaggacuccaaggAACAUUCAACGCUGUCGGUGAGUuugggauuugaaaaaACCACUGACCGUUGACUGUACCuugggguccuua
.((((((((....)))...))))).(((((((((((((.(((.((((((..(((((((.((((...........))))))))))))))))).))).))))))))))))).
.((((((((....)))...))))).(((((((((((((.(((.((((((..(((((((.((((...........))))))))))))))))).))).))))))))))))).
Structure
agaagggcuaucaggccagccuuca A U CU A ggga
gaggacuccaagg ACA UCAACG GUCGGUG GUuu u
||||||||||||| ||| |||||| ||||||| |||| u
uuccugggguuCC UGU AGUUGC CAGUCAC CAaa u
------------------------a A C -- - aaag
Annotation confidence
High
Do you think this miRNA is real?
Comments
This human miRNA was predicted by computational methods using conservation with mouse and Fugu rubripes sequences [1]. Expression of the excised miR has been validated in zebrafish, and the ends mapped by cloning. Landgraf et al. and Lui et al. later verify expression in human [4-5].
Genome context
chr9: 124692442-124692551 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from hsa-mir-181a-2
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Disease association
hsa-mir-181a-2 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-181a-5p
| Accession | MIMAT0000256 |
| Description | Homo sapiens hsa-miR-181a-5p mature miRNA |
| Sequence | 39 - AACAUUCAACGCUGUCGGUGAGU - 61 |
| Evidence |
experimental
cloned [2,4-6] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-181a-2-3p
| Accession | MIMAT0004558 |
| Description | Homo sapiens hsa-miR-181a-2-3p mature miRNA |
| Sequence | 77 - ACCACUGACCGUUGACUGUACC - 98 |
| Evidence |
experimental
cloned [4] |
| Database links |
|
| Predicted targets |
|
References
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