We have generated a dot-bracket structure for each sequence using RNAfold.
Unambiguous secondary structure.
Parsed and ASCII art drawn.
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Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR212 is a microRNA that has been implicated in the regulation of cellular processes in ovarian cancer (OC) cell lines, including proliferation and apoptosis [PMC6995389]. In a meta-analysis, MIR212 was identified among eight microRNAs that showed a significant association with CAG length, suggesting its potential involvement in genetic regulation related to this trinucleotide repeat [PMC5764268]. The findings from the meta-analysis were further supported by data from human brain tissue (BA9), reinforcing the relevance of MIR212 in genetic studies [PMC5764268]. The research on MIR212 contributes to our understanding of its role in OC and possibly other cellular or genetic contexts.
-- accccgcccgga c c -cA U CU C ccc c
cggggc cag gcg cgg CC UGGCU AGACUG UUACUg ggg
|||||| ||| ||| ||| || ||||| |||||| |||||| ||| c
gccccg guc cgc gcc GG ACUGA UCUGAC AAUgac ccc
cc ------------ - a aCC C CC - --u g
Annotation confidence
High
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This human miRNA was predicted by computational methods using conservation with mouse and Fugu rubripes sequences [1]. Expression of the excised miR has been validated in zebrafish, and the 5' end mapped by PCR. The 3' end was not experimentally determined. The sequence maps to human chromosome 17, but its expression has not been experimentally verified in human.