miRBase entry: cel-mir-240

Stem-loop cel-mir-240


Accession
MI0000316
Description
Caenorhabditis elegans cel-mir-240 precursor miRNA mir-240
Gene
family?
RF00804; mir-240

Literature search
7 open access papers mention cel-mir-240
(29 sentences)

Sequence

19156 reads, 255 reads per million, 13 experiments
uuguuagaaacuuuuucaaauCGAGGAUUUUGAGACUAGAAUGCuugaauuguacuagcaUACUGGCCCCCAAAUCUUCGCUuagaaauacaguuca
......(((....((((.((.(((((((((.(.(.((((.(((((...........))))).)))).).).))))))))).)).)))).....))).

Structure
uuguua   -acuu    a  u         U A A    A     ugaa 
      gaa     uuuc aa CGAGGAUUU G G CUAG AUGCu    u
      |||     |||| || ||||||||| | | |||| |||||    u
      cuu     aaag uU GCUUCUAAA C C GGUC Uacga    g
-----a   gacau    a  C         C C C    A     ucau 


Annotation confidence High
Do you think this miRNA is real?

Genome context
chrX: 7882622-7882718 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from cel-mir-240
Name Accession Chromosome Start End Strand Confidence




Database links

Mature cel-miR-240-5p

Accession MIMAT0015116
Description Caenorhabditis elegans cel-miR-240-5p mature miRNA
Sequence 22 - CGAGGAUUUUGAGACUAGAAUGC - 44
Evidence experimental
CLIPseq [4], Illumina [5]
Database links

Mature cel-miR-240-3p

Accession MIMAT0000296
Description Caenorhabditis elegans cel-miR-240-3p mature miRNA
Sequence 61 - UACUGGCCCCCAAAUCUUCGCU - 82
Evidence experimental
cloned [1-2], Northern [1], Illumina [3,5], CLIPseq [4]
Database links
Predicted targets

References

  1. PubMed ID: 12672692
    The microRNAs of Caenorhabditis elegans
    "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
    "Genes Dev (2003) 17:991-1008

  2. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  3. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  4. PubMed ID: 20062054
    Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
    "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
    "Nat Struct Mol Biol (2010) 17:173-179

  5. PubMed ID: 21307183
    Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer
    "Warf MB, Johnson WE, Bass BL"
    "RNA (2011) 17:563-577