miRBase entry: cel-mir-247

Stem-loop cel-mir-247


Accession
MI0000323
Description
Caenorhabditis elegans cel-mir-247 precursor miRNA mir-247
Gene
family?
RF03331; mir-247

Literature search
1 open access papers mention cel-mir-247
(4 sentences)

Sequence

54 reads, 8 reads per million, 10 experiments
auuaccagcuauuuuccaagUAGAGAAAAGUUUCUAAUUACCcaucaugcacaaauguggUGACUAGAGCCUAUUCUCUUCUuggaaaaguggcgacu
.......(((((((((((((.((((((.((.(((((.(((((...(((......))).))))).))))).)).)))))).))))).))))))))....

Structure
auuacca        -     U      A  U     A     cau   gc 
       gcuauuuu ccaag AGAGAA AG UUCUA UUACC   cau  a
       |||||||| ||||| |||||| || ||||| |||||   |||   
       cggugaaa gguUC UCUCUU UC GAGAU AGUgg   gua  c
---ucag        a     U      A  C     C     --u   aa 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
The extents of the dominant mature miRNA species are adjusted here in accordance with a large scale cloning and sequencing study [2].

Genome context
chrX: 4756971-4757068 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from cel-mir-247
Name Accession Chromosome Start End Strand Confidence




Database links

Mature cel-miR-247-5p

Accession MIMAT0015119
Description Caenorhabditis elegans cel-miR-247-5p mature miRNA
Sequence 21 - UAGAGAAAAGUUUCUAAUUACC - 42
Evidence experimental
CLIPseq [4]
Database links

Mature cel-miR-247-3p

Accession MIMAT0000303
Description Caenorhabditis elegans cel-miR-247-3p mature miRNA
Sequence 61 - UGACUAGAGCCUAUUCUCUUCU - 82
Evidence experimental
cloned [1-2], Northern [1], Illumina [3], CLIPseq [4]
Database links
Predicted targets

References

  1. PubMed ID: 12672692
    The microRNAs of Caenorhabditis elegans
    "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
    "Genes Dev (2003) 17:991-1008

  2. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  3. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  4. PubMed ID: 20062054
    Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
    "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
    "Nat Struct Mol Biol (2010) 17:173-179