miRBase entry: cel-mir-249

Stem-loop cel-mir-249


Accession
MI0000325
Description
Caenorhabditis elegans cel-mir-249 precursor miRNA mir-249
Gene
family?
RF00821; mir-249

Literature search
1 open access papers mention cel-mir-249
(6 sentences)

Sequence

557 reads, 16 reads per million, 14 experiments
auacucuugaacgacuAGCAACGCACAAACGUCUUCUGUGcgacaacaucugaauguuugUCACAGGACUUUUGAGCGUUGCCagucgaaagaggaa
...(((((...(((((.(((((((.((((.(((..((((((((..((((....))))))).)))))))).)))).))))))).))))).)))))...

Structure
aua     gaa     A       A    C   UU     -   ca    c 
   cucuu   cgacu GCAACGC CAAA GUC  CUGUG cga  acau u
   |||||   ||||| ||||||| |||| |||  ||||| |||  ||||  
   gagaa   gcuga CGUUGCG GUUU CAG  GACAC guu  ugua g
aag     --a     C       A    U   --     U   --    a 


Annotation confidence Not enough data
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Comments
The extents of the dominant mature miRNA species are adjusted here in accordance with a large scale cloning and sequencing study [2].

Genome context
chrX: 3006440-3006536 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from cel-mir-249
Name Accession Chromosome Start End Strand Confidence




Database links

Mature cel-miR-249-3p

Accession MIMAT0000305
Description Caenorhabditis elegans cel-miR-249-3p mature miRNA
Sequence 61 - UCACAGGACUUUUGAGCGUUGCC - 83
Evidence experimental
cloned [1-2], Illumina [3-4]
Database links
Predicted targets

Mature cel-miR-249-5p

Accession MIMAT0020338
Description Caenorhabditis elegans cel-miR-249-5p mature miRNA
Sequence 17 - AGCAACGCACAAACGUCUUCUGUG - 40
Evidence experimental
Illumina [4]

References

  1. PubMed ID: 12672692
    The microRNAs of Caenorhabditis elegans
    "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
    "Genes Dev (2003) 17:991-1008

  2. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  3. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  4. PubMed ID: 21307183
    Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer
    "Warf MB, Johnson WE, Bass BL"
    "RNA (2011) 17:563-577