miRBase entry: cel-mir-255

Stem-loop cel-mir-255


Accession
MI0000331
Description
Caenorhabditis elegans cel-mir-255 precursor miRNA mir-255
Gene
family?
RF00900; mir-255

Literature search
1 open access papers mention cel-mir-255
(1 sentences)

Sequence

3948 reads, 80 reads per million, 16 experiments
cagugguucgacuaaauuuuggagGUAAGAAAUCUUUGUAGUUCUCcguauugugacgugaAAACUGAAGAGAUUUUUUACAGacuucacaaauuugaaauauauuccug
(((.(((.....(((((((((((((((((((((((((.(((((.(((((......))).)).))))).)))))))))))))...))))).)))))))......))).)))

Structure
   u   -ucgac       -     ---             G     C  -   au 
cag ggu      uaaauuu uggag   GUAAGAAAUCUUU UAGUU UC cgu  u
||| |||      ||||||| |||||   ||||||||||||| ||||| || |||   
guc uua      guuuaaa acuuc   CAUUUUUUAGAGA GUCAA ag gca  g
   c   uauaaa       c     aGA             A     A  u   gu 


Annotation confidence High
Do you think this miRNA is real?
Comments
This precursor sequence was identified computationally using sequence homology with C. briggsae [1]. The mature microRNA was identified later [2].

Genome context
chrV: 5440639-5440748 [+]

Database links

Mature cel-miR-255-3p

Accession MIMAT0004216
Description Caenorhabditis elegans cel-miR-255-3p mature miRNA
Sequence 62 - AAACUGAAGAGAUUUUUUACAG - 83
Evidence experimental
cloned [2], Illumina [3,5], CLIPseq [4]
Database links
Predicted targets

Mature cel-miR-255-5p

Accession MIMAT0020341
Description Caenorhabditis elegans cel-miR-255-5p mature miRNA
Sequence 25 - GUAAGAAAUCUUUGUAGUUCUC - 46
Evidence experimental
Illumina [5]

References

  1. PubMed ID: 12672692
    The microRNAs of Caenorhabditis elegans
    "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
    "Genes Dev (2003) 17:991-1008

  2. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  3. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  4. PubMed ID: 20062054
    Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
    "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
    "Nat Struct Mol Biol (2010) 17:173-179

  5. PubMed ID: 21307183
    Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer
    "Warf MB, Johnson WE, Bass BL"
    "RNA (2011) 17:563-577