Accession
MI0000370
Description
Drosophila melanogaster
dme-mir-281-2 precursor miRNA mir-46
Gene
family?
family?
RF00249;
mir-46
Literature search
13 open access papers mention dme-mir-281-2
(28 sentences)
(28 sentences)
Sequence
2101769
reads,
12674
reads per million, 49 experiments
cgaauugugaaaugAAGAGAGCUAUCCGUCGACAGUcaaguuaagaccgauuguaauacUGUCAUGGAAUUGCUCUCUUUGUauaacauucg
(((((.((...(((((((((((..(((((.((((((..((((......)))).....)))))))))))...)))))))))))...)))))))
(((((.((...(((((((((((..(((((.((((((..((((......)))).....)))))))))))...)))))))))))...)))))))
Structure
u gaa -UA C ---ca aa
cgaau gu augAAGAGAGC UCCGU GACAGU aguu g
||||| || ||||||||||| ||||| |||||| ||||
gcuua ca UGUUUCUCUCG AGGUA CUGUca uuag a
- aua UUA - uaaug cc
Annotation confidence
High
Do you think this miRNA is real?
Comments
miR-281 was reported independently in references [1] and [2]. The sequence in this entry is from reference [2] which identified a 23 nt excised sequence from the 3' arm of the precursor by cloning. Reference [1] reported the reverse complement of this foldback precursor from computational prediction and northern blotting. The predicted mature sequence (5' and 3' ends unknown) from the 3' arm of the reverse complement was named miR-281b in reference [1] and is designated miR-281-2* here.
Genome context
chr2R: 12170153-12170244 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from dme-mir-281-2
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Database links
Mature dme-miR-281-3p
| Accession | MIMAT0000345 |
| Description | Drosophila melanogaster dme-miR-281-3p mature miRNA |
| Sequence | 60 - UGUCAUGGAAUUGCUCUCUUUGU - 82 |
| Evidence |
experimental
Northern [1], cloned [2], 454 [3-4], Illumina [4] |
| Database links |
|
Mature dme-miR-281-2-5p
| Accession | MIMAT0000349 |
| Description | Drosophila melanogaster dme-miR-281-2-5p mature miRNA |
| Sequence | 15 - AAGAGAGCUAUCCGUCGACAGU - 36 |
| Evidence |
experimental
Northern [1], 454 [3-4], Illumina [4] |
| Database links |
|
References
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