miRBase entry: dme-mir-210

Stem-loop dme-mir-210


Accession
MI0000376
Description
Drosophila melanogaster dme-mir-210 precursor miRNA

Literature search
8 open access papers mention dme-mir-210
(29 sentences)

Sequence

236219 reads, 2903 reads per million, 48 experiments
aaaggugcuuauugcAGCUGCUGGCCACUGCACAAGAUuagacuuaagacuCUUGUGCGUGUGACAGCGGCUAUuguaagaggccauagaagcaacagcc
...(((.(((((...((((((((..((((((((((((((........)).))))))))).))).))))))))...)))))..)))......((....)).

Structure
------------aaa   -g     ugc        GC   -         -  aga 
               ggu  cuuau   AGCUGCUG  CAC UGCACAAGA Uu   c
               |||  |||||   ||||||||  ||| ||||||||| ||    
               ccg  gaaug   UCGGCGAC  GUG GCGUGUUCu ag   u
ccgacaacgaagaua   ga     uUA        -A   U         c  aau 


Annotation confidence High
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Comments
This sequence is computationally predicted based on conservation in D. pseudoobscura. The precise 5' or 3' ends are unknown. Northern blotting confirmed that the strand containing the predicted miR is predominantly expressed.

Genome context
chrX: 18128219-18128318 [+]
Clustered miRNAs
1 other miRNA is < 10 kb from dme-mir-210
Name Accession Chromosome Start End Strand Confidence




Database links

Mature dme-miR-210-3p

Accession MIMAT0000355
Description Drosophila melanogaster dme-miR-210-3p mature miRNA
Sequence 52 - CUUGUGCGUGUGACAGCGGCUAU - 74
Evidence experimental
cloned [2], 454 [3-4], Illumina [4]
Database links

Mature dme-miR-210-5p

Accession MIMAT0020816
Description Drosophila melanogaster dme-miR-210-5p mature miRNA
Sequence 16 - AGCUGCUGGCCACUGCACAAGAU - 38
Evidence not_experimental
Database links

References

  1. PubMed ID: 12919683
    The small RNA profile during Drosophila melanogaster development
    "Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T"
    "Dev Cell (2003) 5:337-350

  2. PubMed ID: 17989254
    Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    "Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC"
    "Genome Res (2007) 17:1850-1864

  3. PubMed ID: 17989255
    Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
    "Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M"
    "Genome Res (2007) 17:1865-1879

  4. PubMed ID: 12844358
    Computational identification of Drosophila microRNA genes
    "Lai EC, Tomancak P, Williams RW, Rubin GM"
    "Genome Biol (2003) 4:R42