miRBase entry: dme-mir-9c

Stem-loop dme-mir-9c


Accession
MI0000413
Description
Drosophila melanogaster dme-mir-9c precursor miRNA

Literature search
24 open access papers mention dme-mir-9c
(94 sentences)

Sequence

1225186 reads, 13645 reads per million, 49 experiments
auuuuugcuguuUCUUUGGUAUUCUAGCUGUAGAuuguuucacgcacauuguauaucaucUAAAGCUUUUAUACCAAAGCUCcagcuuaaau
((((..((((...(((((((((...((((.(((((.(....(((.....)))....)))))).))))...)))))))))...))))..))))

Structure
    uu    uuU         UCU    G     u uuuc   c 
auuu  gcug   CUUUGGUAU   AGCU UAGAu g    acg a
||||  ||||   |||||||||   |||| ||||| |    ||| c
uaaa  cgac   GAAACCAUA   UCGA AUcua c    ugu a
    uu    CUC         UUU    A     - uaua   u 


Annotation confidence High
Do you think this miRNA is real?
Comments
Lai et al. predicted this sequence based on conservation in D. pseudoobscura, but did not verify expression [2]. Aravin et al. describe identification and mapping of the ends of the excised sequence by cloning [1].

Genome context
chr2L: 16697924-16698015 [+]
Clustered miRNAs
3 other miRNAs are < 10 kb from dme-mir-9c
Name Accession Chromosome Start End Strand Confidence




Database links

Mature dme-miR-9c-5p

Accession MIMAT0000392
Description Drosophila melanogaster dme-miR-9c-5p mature miRNA
Sequence 13 - UCUUUGGUAUUCUAGCUGUAGA - 34
Evidence experimental
cloned [1], 454 [3-4], Illumina [4]
Database links
Predicted targets

Mature dme-miR-9c-3p

Accession MIMAT0020828
Description Drosophila melanogaster dme-miR-9c-3p mature miRNA
Sequence 61 - UAAAGCUUUUAUACCAAAGCUC - 82
Evidence not_experimental
Database links

References

  1. PubMed ID: 12919683
    The small RNA profile during Drosophila melanogaster development
    "Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T"
    "Dev Cell (2003) 5:337-350

  2. PubMed ID: 17989254
    Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    "Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC"
    "Genome Res (2007) 17:1850-1864

  3. PubMed ID: 17989255
    Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
    "Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M"
    "Genome Res (2007) 17:1865-1879

  4. PubMed ID: 12844358
    Computational identification of Drosophila microRNA genes
    "Lai EC, Tomancak P, Williams RW, Rubin GM"
    "Genome Biol (2003) 4:R42