miRBase entry: dme-mir-125

Stem-loop dme-mir-125


Accession
MI0000417
Description
Drosophila melanogaster dme-mir-125 precursor miRNA

Literature search
20 open access papers mention dme-mir-125
(195 sentences)

Sequence

79053 reads, 2646 reads per million, 49 experiments
gacaugugcaaauguuuguauggcugauUCCCUGAGACCCUAACUUGUGAcuuuuaauaccaguuucACAAGUUUUGAUCUCCGGUAUuggacgcaaacuugcugauguu
(((((..((((..((((((....(((((..((.((((.(..(((((((((...............)))))))))..).)))).)).)))))..))))))))))..)))))

Structure
     gu    au      augg     UC  U    C CU         cuuuua 
gacau  gcaa  guuugu    cugau  CC GAGA C  AACUUGUGA      a
|||||  ||||  ||||||    |||||  || |||| |  |||||||||      u
uugua  cguu  caaacg    gguUA  GG CUCU G  UUGAACAcu      a
     gu    --      --ca     -U  C    A UU         uugacc 


Annotation confidence High
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Genome context
chr2L: 18472315-18472424 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from dme-mir-125
Name Accession Chromosome Start End Strand Confidence




Database links

Mature dme-miR-125-5p

Accession MIMAT0000397
Description Drosophila melanogaster dme-miR-125-5p mature miRNA
Sequence 29 - UCCCUGAGACCCUAACUUGUGA - 50
Evidence experimental
Northern [1-2], 454 [3-4], Illumina [4]
Database links
Predicted targets

Mature dme-miR-125-3p

Accession MIMAT0020831
Description Drosophila melanogaster dme-miR-125-3p mature miRNA
Sequence 68 - ACAAGUUUUGAUCUCCGGUAU - 88
Evidence not_experimental
Database links

References

  1. PubMed ID: 12812784
    Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity
    "Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V"
    "Dev Biol (2003) 259:9-18

  2. PubMed ID: 12919683
    The small RNA profile during Drosophila melanogaster development
    "Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T"
    "Dev Cell (2003) 5:337-350

  3. PubMed ID: 17989254
    Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
    "Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC"
    "Genome Res (2007) 17:1850-1864

  4. PubMed ID: 17989255
    Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
    "Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M"
    "Genome Res (2007) 17:1865-1879