Stem-loop mmu-mir-200a

Accession

MI0000554

Symbol

MGI: Mir200a

Description

Mus musculus mmu-mir-200a precursor miRNA

Gene family

MIPF0000019; mir-8

Literature search

294 open access papers mention mmu-mir-200a
(1995 sentences)

Sequence

169135 reads, 996 reads per million, 99 experiments

cugggccucugugggCAUCUUACCGGACAGUGCUGGAuuucuuggcuugacucUAACACUGUCUGGUAACGAUGUucaaaggugacccac
.(((((.(((.(((((((((((((((((((((.((((..((.......)).)))).))))))))))))).)))))))).))).).)))).

Structure

c    - c   g        -             C    uu  uu 
 uggg c ucu ugggCAUC UUACCGGACAGUG UGGA  uc  g
 |||| | ||| |||||||| ||||||||||||| ||||  ||  g
 accc g gga acuUGUAG AAUGGUCUGUCAC AUcu  ag  c
c    a u   a        C             A    -c  uu 

Annotation confidence High

Genome context

chr4: 156054896-156054985 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mmu-mir-200a

Mature mmu-miR-200a-5p

• Accession: MIMAT0004619
• Description: Mus musculus mmu-miR-200a-5p mature miRNA
• Sequence: 16 - CAUCUUACCGGACAGUGCUGGA - 37
• Evidence: experimental ; cloned [2], Illumina [3-4]

Mature mmu-miR-200a-3p

• Accession: MIMAT0000519
• Description: Mus musculus mmu-miR-200a-3p mature miRNA
• Sequence: 54 - UAACACUGUCUGGUAACGAUGU - 75
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12554859
   New microRNAs from mouse and human
   "Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T"
   "RNA (2003) 9:175-179


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009