Stem-loop mmu-mir-32

Accession

MI0000691

Symbol

MGI: Mir32

Description

Mus musculus mmu-mir-32 precursor miRNA mir-32

Gene
family

RF00666; mir-32

Literature search

40 open access papers mention mmu-mir-32
(375 sentences)

Sequence

13306 reads, 208 reads per million, 104 experiments

ggagaUAUUGCACAUUACUAAGUUGCAuguugucacggccucaaugCAAUUUAGUGUGUGUGAUAUUuuc
(((((((((((((((.(((((((((((((..((....))..).)))))))))))))))))))))))))))

Structure

               U            - uu  c 
ggagaUAUUGCACAU ACUAAGUUGCAu g  gu a
||||||||||||||| |||||||||||| |  ||  
cuuUUAUAGUGUGUG UGAUUUAACgua c  cg c
               -            a uc  g 

Annotation confidence High

Comments

Mouse mir-32 is predicted [3] based on homology to a cloned miR from human (MIR:MI0000090) [1]. Its expression in mouse was later independently verified [2]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [4].

Genome context

chr4: 56895229-56895298 [-]

Mature mmu-miR-32-5p

• Accession: MIMAT0000654
• Description: Mus musculus mmu-miR-32-5p mature miRNA
• Sequence: 6 - UAUUGCACAUUACUAAGUUGCA - 27
• Evidence: experimental ; cloned [2,4], Illumina [5,7]

Mature mmu-miR-32-3p

• Accession: MIMAT0017050
• Description: Mus musculus mmu-miR-32-3p mature miRNA
• Sequence: 47 - CAAUUUAGUGUGUGUGAUAUU - 67
• Evidence: experimental ; 454 [6], Illumina [7]

References

1. PubMed ID: 11679670
   Identification of novel genes coding for small expressed RNAs
   "Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T"
   "Science (2001) 294:853-858


2. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


3. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


4. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


5. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


6. PubMed ID: 15634332
   New human and mouse microRNA genes found by homology search
   "Weber MJ"
   "FEBS J (2005) 272:59-73


7. PubMed ID: 20668074
   Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68
   "Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H"
   "J Virol (2010) 84:10266-10275