Stem-loop mmu-mir-219a-1

Accession

MI0000702

Symbol

MGI: Mir219a-1

Description

Mus musculus mmu-mir-219a-1 precursor miRNA mir-219

Gene
family

RF00251; mir-219

Literature search

47 open access papers mention mmu-mir-219a-1
(479 sentences)

Sequence

30273 reads, 180 reads per million, 100 experiments

ccgucccgggccgcggcuccUGAUUGUCCAAACGCAAUUCUcgagucucuggcuccggccgAGAGUUGCGUCUGGACGUCCCGagccgccgcccccaaaccucgaggggg
...((((((((.(((((((..(((.(((((.((((((((((((.(((.........))))))))))))))).))))))))..))))))).))))...........)))).

Structure

ccg    -----------    c       cU   U     A            a   ucu 
   uccc           gggc gcggcuc  GAU GUCCA ACGCAAUUCUcg guc   g
   ||||           |||| |||||||  ||| ||||| |||||||||||| |||   g
   gggg           cccg cgccgaG  CUG CAGGU UGCGUUGAGAgc cgg   c
--g    agcuccaaacc    c       CC   -     C            -   ccu 

Annotation confidence Medium

Genome context

chr17: 34024983-34025092 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-219a-1

Mature mmu-miR-219a-5p

• Accession: MIMAT0000664
• Description: Mus musculus mmu-miR-219a-5p mature miRNA
• Sequence: 21 - UGAUUGUCCAAACGCAAUUCU - 41
• Evidence: experimental ; Illumina [3-4]

Mature mmu-miR-219a-1-3p

• Accession: MIMAT0017055
• Description: Mus musculus mmu-miR-219a-1-3p mature miRNA
• Sequence: 62 - AGAGUUGCGUCUGGACGUCCCG - 83
• Evidence: experimental ; Illumina [5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12624257
   Vertebrate microRNA genes
   "Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP"
   "Science (2003) 299:1540


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


5. PubMed ID: 15634332
   New human and mouse microRNA genes found by homology search
   "Weber MJ"
   "FEBS J (2005) 272:59-73