Stem-loop mmu-mir-377

Accession

MI0000794

Symbol

MGI: Mir377

Description

Mus musculus mmu-mir-377 precursor miRNA

Literature search

22 open access papers mention mmu-mir-377
(112 sentences)

Sequence

27397 reads, 341 reads per million, 72 experiments

ugagcAGAGGUUGCCCUUGGUGAAUUCgcuuuauugauguugaAUCACACAAAGGCAACUUUUGUuug
.((((((((((((((.(((((((.(((((.........).)))))))).))).)))))))))))))).

Structure

u              C   -    A    - uuu 
 gagcAGAGGUUGCC UUG GUGA UUCg c   a
 |||||||||||||| ||| |||| |||| |   u
 uuUGUUUUCAACGG AAC CACU Aagu g   u
g              A   A    -    u uag 

Annotation confidence Medium

Genome context

chr12: 109740510-109740577 [+]

Clustered miRNAs

13 other miRNAs are < 10 kb from mmu-mir-377

Mature mmu-miR-377-5p

• Accession: MIMAT0017079
• Description: Mus musculus mmu-miR-377-5p mature miRNA
• Sequence: 6 - AGAGGUUGCCCUUGGUGAAUUC - 27
• Evidence: experimental ; Illumina [5]

Mature mmu-miR-377-3p

• Accession: MIMAT0000741
• Description: Mus musculus mmu-miR-377-3p mature miRNA
• Sequence: 44 - AUCACACAAAGGCAACUUUUGU - 65
• Evidence: experimental ; cloned [1-3], Illumina [4-5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


5. PubMed ID: 16274478
   Identification of clustered microRNAs using an ab initio prediction method
   Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
   BMC Bioinformatics (2005) 6:267