miRBase entry: rno-mir-146a

Stem-loop rno-mir-146a


Accession
MI0000919
Description
Rattus norvegicus rno-mir-146a precursor miRNA

Literature search
107 open access papers mention rno-mir-146a
(1159 sentences)

Sequence

176571 reads, 3964 reads per million, 496 experiments
uguguauccucagcucUGAGAACUGAAUUCCAUGGGUUauagcaaugucagACCUGUGAAGUUCAGUUCUUUagcugggauagcucuaucgucau
.((.(((((.(((((..((((((((((((.(((((((((((....)))..)))))))).)))))))))))).))))))))))))...........

Structure
----------u  g     u     cU            C        --   g 
           gu uaucc cagcu  GAGAACUGAAUU CAUGGGUU  aua c
           || ||||| |||||  |||||||||||| ||||||||  |||  
           cg auagg gucga  UUCUUGACUUGA GUGUCCAg  ugu a
uacugcuaucu  -     -     -U            A        ac   a 


Annotation confidence High
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Genome context
chr10: 28962476-28962570 [-]

Database links

Mature rno-miR-146a-5p

Accession MIMAT0000852
Description Rattus norvegicus rno-miR-146a-5p mature miRNA
Sequence 17 - UGAGAACUGAAUUCCAUGGGUU - 38
Evidence experimental
cloned [1-3], SOLiD [4]

Mature rno-miR-146a-3p

Accession MIMAT0017132
Description Rattus norvegicus rno-miR-146a-3p mature miRNA
Sequence 52 - ACCUGUGAAGUUCAGUUCUUU - 72
Evidence experimental
SOLiD [4]

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 16766679
    Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
    "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
    "Genes Dev (2006) 20:1732-1743

  3. PubMed ID: 20403161
    Small RNA expression and strain specificity in the rat
    Linsen SE, de Wit E, de Bruijn E, Cuppen E
    BMC Genomics (2010) 11:249

  4. PubMed ID: 15345052
    Microarray analysis of microRNA expression in the developing mammalian brain
    Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
    Genome Biol (2004) 5:R68