Stem-loop rno-mir-183

Accession

MI0000928

Description

Rattus norvegicus rno-mir-183 precursor miRNA

Literature search

35 open access papers mention rno-mir-183
(109 sentences)

Sequence

489895 reads, 834 reads per million, 491 experiments

ccagagagugugacuccuguccugugUAUGGCACUGGUAGAAUUCACUgugaacagucucggucagUGAAUUACCGAAGGGCCAUAAacagagcagagacagauccgcga
...(.(.((.((.(((.(((.((((.((((((.((((((..(((((((((((......)))..))))))))))))..)).)))))).)))).)))))).)).)).).)..

Structure

cca a a  g  a   c   c    g      A  --    GA        --   ac 
   g g gu ug cuc ugu cugu UAUGGC CU  GGUA  AUUCACUg  uga  a
   | | || || ||| ||| |||| |||||| ||  ||||  ||||||||  |||   
   c c ua ac gag acg gaca AUACCG GA  CCAU  UAAGUgac  gcu  g
-ag g c  g  a   -   a    A      G  AG    --        ug   cu 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

chr4: 57463569-57463678 [-]

Clustered miRNAs

3 other miRNAs are < 10 kb from rno-mir-183

Mature rno-miR-183-5p

• Accession: MIMAT0000860
• Description: Rattus norvegicus rno-miR-183-5p mature miRNA
• Sequence: 27 - UAUGGCACUGGUAGAAUUCACU - 48
• Evidence: experimental ; cloned [1-2], SOLiD [3]

Mature rno-miR-183-3p

• Accession: MIMAT0017141
• Description: Rattus norvegicus rno-miR-183-3p mature miRNA
• Sequence: 67 - UGAAUUACCGAAGGGCCAUAA - 87
• Evidence: experimental ; SOLiD [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


3. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249