Stem-loop hsa-mir-429

Accession

MI0001641

Symbol

HGNC: MIR429

Description

Homo sapiens hsa-mir-429 precursor miRNA mir-8

Gene
family

RF00241; mir-8

Literature search

481 open access papers mention hsa-mir-429
(1440 sentences)

Sequence

22336 reads, 48.0 reads per million, 152 experiments

cgccggccgaugggcGUCUUACCAGACAUGGUUAGACcuggcccucugucUAAUACUGUCUGGUAAAACCGUccauccgcugc
...((((.((((((((..((((((((((..(((((((..........)))))))..))))))))))...)))))))).)))).

Structure

cgc    c        -UC          UG       cugg 
   cggc gaugggcG   UUACCAGACA  GUUAGAC    c
   |||| ||||||||   ||||||||||  |||||||     
   gucg cuaccUGC   AAUGGUCUGU  UAAUcug    c
--c    c        CAA          CA       ucuc 

Annotation confidence High

Comments

Xie et al. [1] refer to this sequence by the internal identifier MIR201. The sequence is unrelated to mouse mir-201 (MIR:MI0000244).

Genome context

chr1: 1169005-1169087 [+]

Clustered miRNAs

2 other miRNAs are < 10 kb from hsa-mir-429

Disease association

hsa-mir-429 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-429-5p

• Accession: MIMAT0060796
• Description: Homo sapiens hsa-miR-429-5p mature miRNA
• Sequence: 16 - GUCUUACCAGACAUGGUUAGAC - 37
• Evidence: experimental ; cloned [1-4]

Mature hsa-miR-429-3p

• Accession: MIMAT0001536
• Description: Homo sapiens hsa-miR-429-3p mature miRNA
• Sequence: 51 - UAAUACUGUCUGGUAAAACCGU - 72
• Evidence: experimental ; cloned [1-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


3. PubMed ID: 15891114
   Clustering and conservation patterns of human microRNAs
   "Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H"
   "Nucleic Acids Res (2005) 33:2697-2706


4. PubMed ID: 15735639
   Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
   "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
   "Nature (2005) 434:338-345