Stem-loop mghv-mir-M1-2

Accession

MI0001670

Description

Mouse gammaherpesvirus 68 mghv-mir-M1-2 precursor miRNA

Sequence

gAGAGGGGGAGUGUGUGGUCUGUagagagacaugaguugaucggCAGACCCCCUCUCCCCCUCUUU
(((((((((((.(.(.(((((((.((..(((....)))..)).))))))).)).))))))))))).

Structure

-           U U U       a  ga   a 
 gAGAGGGGGAG G G GGUCUGU ga  gac u
 ||||||||||| | | ||||||| ||  |||  
 UUCUCCCCCUC C C CCAGACg cu  uug g
U           U - C       g  ag   a 

Annotation confidence Not enough data

Genome context

U97553: 562-627 [+]

Clustered miRNAs

14 other miRNAs are < 10 kb from mghv-mir-M1-2

Mature mghv-miR-M1-2-5p

• Accession: MIMAT0017186
• Description: Mouse gammaherpesvirus 68 mghv-miR-M1-2-5p mature miRNA
• Sequence: 2 - AGAGGGGGAGUGUGUGGUCUGU - 23
• Evidence: experimental ; 454 [4]

Mature mghv-miR-M1-2-3p

• Accession: MIMAT0001565
• Description: Mouse gammaherpesvirus 68 mghv-miR-M1-2-3p mature miRNA
• Sequence: 45 - CAGACCCCCUCUCCCCCUCUUU - 66
• Evidence: experimental ; cloned [1-3], 454 [4], Illumina [5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20668074
   Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68
   "Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H"
   "J Virol (2010) 84:10266-10275


3. PubMed ID: 15782219
   Identification of microRNAs of the herpesvirus family
   "Pfeffer S, Sewer A, Lagos-Quintana M, Sheridan R, Sander C, Grasser FA, van Dyk LF, Ho CK, Shuman S, Chien M, Russo JJ, Ju J, Randall G, Lindenbach BD, Rice CM, Simon V, Ho DD, Zavolan M, Tuschl T"
   "Nat Methods (2005) 2:269-276


4. PubMed ID: 19948768
   Mature and functional viral miRNAs transcribed from novel RNA polymerase III promoters
   "Diebel KW, Smith AL, van Dyk LF"
   "RNA (2010) 16:170-185


5. PubMed ID: 20660200
   Identification of novel microRNA-like molecules generated from herpesvirus and host tRNA transcripts
   "Reese TA, Xia J, Johnson LS, Zhou X, Zhang W, Virgin HW"
   "J Virol (2010) 84:10344-10353