Stem-loop mmu-mir-466a

Accession

MI0002401

Description

Mus musculus mmu-mir-466a precursor miRNA mir-466

Gene
family

RF04052; mir-466

Literature search

28 open access papers mention mmu-mir-466a
(125 sentences)

Sequence

19070 reads, 321 reads per million, 100 experiments

uauauguguuUAUGUGUGUGUACAUGUACAUAugugaauaugauauccaUAUACAUACACGCACACAUAAGAc
..(((((((...((((((((((.((((((((((....))))).))..))).)))))))))).)))))))....

Structure

--ua       uUA          C   --  -     g 
    uaugugu   UGUGUGUGUA AUG  UA CAUAu u
    |||||||   |||||||||| |||  || |||||  
    AUACACA   GCACAUACAU Uac  au guaua g
cAGA       --C          A   cu  a     a 

Annotation confidence Not enough data

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

chr2: 10507918-10507990 [+]

Clustered miRNAs

25 other miRNAs are < 10 kb from mmu-mir-466a

Mature mmu-miR-466a-5p

• Accession: MIMAT0004759
• Description: Mus musculus mmu-miR-466a-5p mature miRNA
• Sequence: 11 - UAUGUGUGUGUACAUGUACAUA - 32
• Evidence: experimental ; cloned [2], Illumina [3-4]

Mature mmu-miR-466a-3p

• Accession: MIMAT0002107
• Description: Mus musculus mmu-miR-466a-3p mature miRNA
• Sequence: 50 - UAUACAUACACGCACACAUAAGA - 72
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 15901636
   MicroRNA Mirn122a reduces expression of the posttranscriptionally regulated germ cell transition protein 2 (Tnp2) messenger RNA (mRNA) by mRNA cleavage
   "Yu Z, Raabe T, Hecht NB"
   "Biol Reprod (2005) 73:427-433