Stem-loop mmu-mir-470

Accession

MI0002405

Symbol

MGI: Mir470

Description

Mus musculus mmu-mir-470 precursor miRNA mir-890

Gene
family

RF04280; mir-890

Literature search

11 open access papers mention mmu-mir-470
(20 sentences)

Sequence

202579 reads, 4587 reads per million, 51 experiments

cagugcucUUCUUGGACUGGCACUGGUGAGUuaaacuaaauacAACCAGUACCUUUCUGAGAAGAguaaagcuca
...(((((((((((((..((.((((((..((..........)).)))))).))..))))))))))))).......

Structure

----cag             CU  C      GA  uaaa 
       ugcucUUCUUGGA  GG ACUGGU  GU    c
       |||||||||||||  || ||||||  ||     
       augAGAAGAGUCU  CC UGACCA  ca    u
acucgaa             UU  A      -A  uaaa 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

chrX: 66813951-66814025 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mmu-mir-470

Mature mmu-miR-470-5p

• Accession: MIMAT0002111
• Description: Mus musculus mmu-miR-470-5p mature miRNA
• Sequence: 9 - UUCUUGGACUGGCACUGGUGAGU - 31
• Evidence: experimental ; cloned [1-3], Illumina [4-5]

Mature mmu-miR-470-3p

• Accession: MIMAT0004760
• Description: Mus musculus mmu-miR-470-3p mature miRNA
• Sequence: 44 - AACCAGUACCUUUCUGAGAAGA - 65
• Evidence: experimental ; cloned [3], Illumina [4-5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


5. PubMed ID: 15901636
   MicroRNA Mirn122a reduces expression of the posttranscriptionally regulated germ cell transition protein 2 (Tnp2) messenger RNA (mRNA) by mRNA cleavage
   "Yu Z, Raabe T, Hecht NB"
   "Biol Reprod (2005) 73:427-433