Stem-loop hsa-mir-486-1

Accession

MI0002470

Symbol

HGNC: MIR486-1

Description

Homo sapiens hsa-mir-486-1 precursor miRNA mir-486

Gene
family

RF00784; mir-486

Literature search

182 open access papers mention hsa-mir-486-1
(1114 sentences)

Sequence

131005 reads, 739 reads per million, 108 experiments

gcaUCCUGUACUGAGCUGCCCCGAGgcccuucaugcugcccagcuCGGGGCAGCUCAGUACAGGAUac
..(((((((((((((((((((((((..................)))))))))))))))))))))))..

Structure

gc                       gcccuuca 
  aUCCUGUACUGAGCUGCCCCGAG        u
  |||||||||||||||||||||||         
  UAGGACAUGACUCGACGGGGCuc        g
ca                       gacccguc 

Annotation confidence Medium

Genome context

chr8: 41660441-41660508 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-486-1

Disease association

hsa-mir-486-1 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-486-5p

• Accession: MIMAT0002177
• Description: Homo sapiens hsa-miR-486-5p mature miRNA
• Sequence: 4 - UCCUGUACUGAGCUGCCCCGAG - 25
• Evidence: experimental ; Illumina [1]

Mature hsa-miR-486-3p

• Accession: MIMAT0004762
• Description: Homo sapiens hsa-miR-486-3p mature miRNA
• Sequence: 46 - CGGGGCAGCUCAGUACAGGAU - 66
• Evidence: experimental ; Illumina [1]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15978578
   Identification of human fetal liver miRNAs by a novel method
   "Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X"
   "FEBS Lett (2005) 579:3849-3854