Mature hsa-miR-486-3p

• Accession: MIMAT0004762
• Description: hsa-miR-486-3p mature miRNA
• Hairpins:
  • hsa-mir-486-1
  • hsa-mir-486-2
• Sequence: CGGGGCAGCUCAGUACAGGAU
• Evidence: experimental ; Illumina [1]

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Qualifier	GO term	Evidence	Reference	Annotation Extension
acts_upstream_of	GO:0008285 negative regulation of cell population proliferation	ECO:0000314 direct assay evidence used in manual assertion	PMID:24778011
enables	GO:0003730 mRNA 3'-UTR binding	ECO:0000314 direct assay evidence used in manual assertion	PMID:24778011	has_input UniProtKB:P12643
enables	GO:1903231 mRNA base-pairing translational repressor activity	ECO:0000314 direct assay evidence used in manual assertion	PMID:24778011	has_input UniProtKB:P12643
enables	GO:1903231 mRNA base-pairing translational repressor activity	ECO:0000314 direct assay evidence used in manual assertion	PMID:25857263	has_input UniProtKB:O75444
involved_in	GO:0030854 positive regulation of granulocyte differentiation	ECO:0000315 mutant phenotype evidence used in manual assertion	PMID:25857263
involved_in	GO:0035195 miRNA-mediated post-transcriptional gene silencing	ECO:0000314 direct assay evidence used in manual assertion	PMID:24778011	has_input UniProtKB:P12643
involved_in	GO:0035279 miRNA-mediated gene silencing by mRNA destabilization	ECO:0000314 direct assay evidence used in manual assertion	PMID:25857263	has_input UniProtKB:O75444
involved_in	GO:0045648 positive regulation of erythrocyte differentiation	ECO:0000315 mutant phenotype evidence used in manual assertion	PMID:25857263
involved_in	GO:0045650 negative regulation of macrophage differentiation	ECO:0000315 mutant phenotype evidence used in manual assertion	PMID:25857263
involved_in	GO:0045653 negative regulation of megakaryocyte differentiation	ECO:0000315 mutant phenotype evidence used in manual assertion	PMID:25857263
located_in	GO:0005615 extracellular space	ECO:0007005 high throughput direct assay evidence used in manual assertion	PMID:26646931	part_of UBERON:0001969