Stem-loop mml-mir-141

Accession

MI0002485

Description

Macaca mulatta mml-mir-141 precursor miRNA mir-8

Gene
family

RF00241; mir-8

Literature search

8 open access papers mention mml-mir-141
(10 sentences)

Sequence

278725 reads, 413.0 reads per million, 134 experiments

uggccggcccugggucCAUCUUCCAGUACAGUGUUGGAuggucuaauugugaagcuccUAACACUGUCUGGUAAAGAUGGCccccgggucgguuu
.(((((((((.(((.(((((((((((.(((((((((((...((.......))...))).))))))))))))..))))))).))).))))))))).

Structure

u         u   u       --    U        -   ugg  ua 
 ggccggccc ggg cCAUCUU  CCAG ACAGUGUU GGA   uc  a
 ||||||||| ||| |||||||  |||| |||||||| |||   ||  u
 uuggcuggg ccc GGUAGAA  GGUC UGUCACAA ccu   ag  u
u         c   C       AU    -        U   cga  ug 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

11: 7137462-7137556 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from mml-mir-141

Mature mml-miR-141-5p

• Accession: MIMAT0026561
• Description: Macaca mulatta mml-miR-141-5p mature miRNA
• Sequence: 17 - CAUCUUCCAGUACAGUGUUGGA - 38
• Evidence: experimental ; Illumina [2]

Mature mml-miR-141-3p

• Accession: MIMAT0002196
• Description: Macaca mulatta mml-miR-141-3p mature miRNA
• Sequence: 59 - UAACACUGUCUGGUAAAGAUGGC - 81
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45