Stem-loop mml-mir-215

Accession

MI0003025

Description

Macaca mulatta mml-mir-215 precursor miRNA mir-192

Gene
family

RF00130; mir-192

Literature search

4 open access papers mention mml-mir-215
(4 sentences)

Sequence

2639845 reads, 2719.0 reads per million, 150 experiments

aucauuaagaaaugguauacaggaaaAUGACCUAUGAAUUGACAGACAcuauagcugaguuugUCUGUCAUUUCUUUAGGCCAAUauucuguaugacugugcuacuucaa
.......((..(((((((((((((...((.((((.(((.(((((((((..((......)).))))))))).)))..)))).))...)))))))).))))).)).......

Structure

aucauua  aa     -        aaA  A    -U   U         cu  ag 
       ag  auggu auacagga   UG CCUA  GAA UGACAGACA  au  c
       ||  ||||| ||||||||   || ||||  ||| |||||||||  ||   
       uc  uguca uaugucuu   AC GGAU  CUU ACUGUCUgu  ug  u
aacuuca  -g     g        aUA  C    UU   U         -u  ag 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

1: 77682784-77682893 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mml-mir-215

Mature mml-miR-215-5p

• Accession: MIMAT0002728
• Description: Macaca mulatta mml-miR-215-5p mature miRNA
• Sequence: 27 - AUGACCUAUGAAUUGACAGACA - 48
• Evidence: experimental ; Illumina [2]

Mature mml-miR-215-3p

• Accession: MIMAT0026598
• Description: Macaca mulatta mml-miR-215-3p mature miRNA
• Sequence: 64 - UCUGUCAUUUCUUUAGGCCAAU - 85
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45