Stem-loop mml-mir-106b

Accession

MI0003073

Description

Macaca mulatta mml-mir-106b precursor miRNA mir-17

Gene
family

RF00051; mir-17

Literature search

1 open access papers mention mml-mir-106b
(1 sentences)

Sequence

52364 reads, 422 reads per million, 8 experiments

ccugcuggggcUAAAGUGCUGACAGUGCAGAUagugguccucuccgugcuACCGCACUGUGGGUACUUGCUGcuccagcagg
(((((((((((..(((((((.(((((((.(.((((((......))..))))).))))))).)))))))...)))))))))))

Structure

           -UA       G       A A    --  uc 
ccugcuggggc   AAGUGCU ACAGUGC G Uagu  gg  c
|||||||||||   ||||||| ||||||| | ||||  ||   
ggacgaccucG   UUCAUGG UGUCACG C Aucg  cc  u
           UCG       G       C -    ug  uc 

Annotation confidence Medium

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr3: 125615402-125615483 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mml-mir-106b

Mature mml-miR-106b-5p

• Accession: MIMAT0002772
• Description: Macaca mulatta mml-miR-106b-5p mature miRNA
• Sequence: 12 - UAAAGUGCUGACAGUGCAGAU - 32
• Evidence: experimental ; Illumina [2]

Mature mml-miR-106b-3p

• Accession: MIMAT0026601
• Description: Macaca mulatta mml-miR-106b-3p mature miRNA
• Sequence: 51 - ACCGCACUGUGGGUACUUGCUG - 72
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45