Stem-loop mml-mir-93

Accession

MI0003074

Description

Macaca mulatta mml-mir-93 precursor miRNA mir-17

Gene
family

RF00051; mir-17

Literature search

3 open access papers mention mml-mir-93
(3 sentences)

Sequence

144386 reads, 1590 reads per million, 9 experiments

cugggggcuccAAAGUGCUGUUCGUGCAGGUAGugugauuaaccgaccuACUGCUGAGCUAGCACUUCCCGagcccccag
((((((((((..((((((((((((.((((.(((.((.........)))))))))))))).)))))))...))))))))))

Structure

          -cA       -     U    G   u  gau 
cugggggcuc   AAGUGCU GUUCG GCAG UAG gu   u
||||||||||   ||||||| ||||| |||| ||| ||   a
gacccccgaG   UUCACGA CGAGU CGUC Auc ca   a
          CCC       U     -    -   -  gcc 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr3: 125615179-125615258 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mml-mir-93

Mature mml-miR-93-5p

• Accession: MIMAT0002773
• Description: Macaca mulatta mml-miR-93-5p mature miRNA
• Sequence: 12 - AAAGUGCUGUUCGUGCAGGUAG - 33
• Evidence: experimental ; Illumina [2]

Mature mml-miR-93-3p

• Accession: MIMAT0026602
• Description: Macaca mulatta mml-miR-93-3p mature miRNA
• Sequence: 50 - ACUGCUGAGCUAGCACUUCCCG - 71
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45