miRBase entry: mml-mir-19b-2

Stem-loop mml-mir-19b-2

Accession

MI0003108

Description

Macaca mulatta mml-mir-19b-2 precursor miRNA mir-19

Gene
family?

RF00245; mir-19

Literature search

3 open access papers mention mml-mir-19b-2
(5 sentences)

Sequence

396653 reads, 922.0 reads per million, 152 experiments

acauugcuacuuacaauuAGUUUUGCAGGUUUGCAUuucagcguauauauguauauguggcUGUGCAAAUCCAUGCAAAACUGAuugugauaaugu
((((((....((((((((((((((((((((((((((....(((((((....)))))))....))))))).)).)))))))))))))))))))))))

Structure

      cuac                 -  -       uuca       u 
acauug    uuacaauuAGUUUUGCA GG UUUGCAU    gcguaua a
||||||    ||||||||||||||||| || |||||||    |||||||  
uguaau    aguguuAGUCAAAACGU CC AAACGUG    uguauau u
      ----                 A  U       Ucgg       g

Annotation confidence High

Do you think this miRNA is real?

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

X: 130425360-130425455 [-]

Clustered miRNAs

5 other miRNAs are < 10 kb from mml-mir-19b-2

Name	Accession	Chromosome	Start	End	Strand	Confidence

Database links

Mature mml-miR-19b-2-5p

Accession	MIMAT0051612
Description	Macaca mulatta mml-miR-19b-2-5p mature miRNA
Sequence	19 - AGUUUUGCAGGUUUGCAU - 36
Evidence	not_experimental

Mature mml-miR-19b-3p

Accession	MIMAT0002705
Description	Macaca mulatta mml-miR-19b-3p mature miRNA
Sequence	62 - UGUGCAAAUCCAUGCAAAACUGA - 84
Evidence	not_experimental
Database links
Predicted targets

References

PubMed ID: 15652478
Phylogenetic shadowing and computational identification of human microRNA genes
"Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
"Cell (2005) 120:21-24