Stem-loop hsa-mir-498

Accession

MI0003142

Symbol

HGNC: MIR498

Description

Homo sapiens hsa-mir-498 precursor miRNA mir-498

Gene
family

RF00958; mir-498

Literature search

21 open access papers mention hsa-mir-498
(44 sentences)

Sequence

57 reads, 14 reads per million, 18 experiments

aacccuccuugggaagugaagcucaggcugugaUUUCAAGCCAGGGGGCGUUUUUCuauaacuggaugaAAAGCACCUCCAGAGCUUGAAGCucacaguuugagagcaaucgucuaaggaaguu
.....((((((((........(((((((((((((((((((((.(((((.(((((((...........))))))).))))).).)))))))).))))))))))))........))))))))....

Structure

aaccc        aagugaag            -        - A     C       uaua 
     uccuuggg        cucaggcuguga UUUCAAGC C GGGGG GUUUUUC    a
     ||||||||        |||||||||||| |||||||| | ||||| |||||||    c
     aggaaucu        gaguuugacacu GAAGUUCG G CCUCC CGAAAag    u
-uuga        gcuaacga            C        A A     A       uagg 

Annotation confidence Not enough data

Genome context

chr19: 53674197-53674320 [+]

Clustered miRNAs

7 other miRNAs are < 10 kb from hsa-mir-498

Disease association

hsa-mir-498 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-498-5p

• Accession: MIMAT0002824
• Description: Homo sapiens hsa-miR-498-5p mature miRNA
• Sequence: 34 - UUUCAAGCCAGGGGGCGUUUUUC - 56
• Evidence: experimental ; array-cloned [1], cloned [2]

Mature hsa-miR-498-3p

• Accession: MIMAT0037323
• Description: Homo sapiens hsa-miR-498-3p mature miRNA
• Sequence: 70 - AAAGCACCUCCAGAGCUUGAAGC - 92
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15965474
   Identification of hundreds of conserved and nonconserved human microRNAs
   "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
   "Nat Genet (2005) 37:766-770


3. PubMed ID: 25822230
   Selective microRNA-Offset RNA expression in human embryonic stem cells
   Asikainen S, Heikkinen L, Juhila J, Holm F, Weltner J, Trokovic R, Mikkola M, Toivonen S, Balboa D, Lampela R, Icay K, Tuuri T, Otonkoski T, Wong G, Hovatta O
   PLoS One (2015) 10:e0116668