Stem-loop hsa-mir-542

Accession

MI0003686

Symbol

HGNC: MIR542

Description

Homo sapiens hsa-mir-542 precursor miRNA mir-542

Gene
family

RF00755; mir-542

Literature search

52 open access papers mention hsa-mir-542
(251 sentences)

Sequence

41785 reads, 402 reads per million, 112 experiments

cagaucucagacaucUCGGGGAUCAUCAUGUCACGAGAuaccagugugcacuUGUGACAGAUUGAUAACUGAAAggucugggagccacucaucuuca
....((((((((...((((..((((...(((((((((.(((....)))..)))))))))...))))..))))...))))))))..............

Structure

----------caga        auc    GG    UCA         -A   c 
              ucucagac   UCGG  AUCA   UGUCACGAG  uac a
              ||||||||   ||||  ||||   |||||||||  |||  
              agggucug   AGUC  UAGU   ACAGUGUuc  gug g
acuucuacucaccg        gAA    AA    UAG         ac   u 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chrX: 134541341-134541437 [-]

Clustered miRNAs

5 other miRNAs are < 10 kb from hsa-mir-542

Disease association

hsa-mir-542 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-542-5p

• Accession: MIMAT0003340
• Description: Homo sapiens hsa-miR-542-5p mature miRNA
• Sequence: 16 - UCGGGGAUCAUCAUGUCACGAGA - 38
• Evidence: experimental ; cloned [1-3]

Mature hsa-miR-542-3p

• Accession: MIMAT0003389
• Description: Homo sapiens hsa-miR-542-3p mature miRNA
• Sequence: 53 - UGUGACAGAUUGAUAACUGAAA - 74
• Evidence: experimental ; cloned [1-2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


3. PubMed ID: 16274478
   Identification of clustered microRNAs using an ab initio prediction method
   Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
   BMC Bioinformatics (2005) 6:267