Stem-loop mmu-mir-301b

Accession

MI0004122

Symbol

MGI: Mir301b

Description

Mus musculus mmu-mir-301b precursor miRNA

Literature search

24 open access papers mention mmu-mir-301b
(57 sentences)

Sequence

16599 reads, 130 reads per million, 91 experiments

uuuccugcuggcugcggguGCUCUGACUAGGUUGCACUACUgugcugugagaagCAGUGCAAUGGUAUUGUCAAAGCaucugggaccagccucgaag
.(((..(((((.(.((((((((.((((...((((((((.....(((......)))))))))))......)))).)))))))).).)))))...))).

Structure

u   -cu     c g        C    ---UAG        ACUgu   gu 
 uuc   gcugg u cggguGCU UGAC      GUUGCACU     gcu  g
 |||   ||||| | |||||||| ||||      ||||||||     |||   
 aag   cgacc g gucuaCGA ACUG      UAACGUGA     Cga  a
g   cuc     a g        A    UUAUGG        -----   ag 

Annotation confidence Medium

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr16: 17124400-17124496 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-301b

Mature mmu-miR-301b-5p

• Accession: MIMAT0017232
• Description: Mus musculus mmu-miR-301b-5p mature miRNA
• Sequence: 20 - GCUCUGACUAGGUUGCACUACU - 41
• Evidence: experimental ; Illumina [5]

Mature mmu-miR-301b-3p

• Accession: MIMAT0004186
• Description: Mus musculus mmu-miR-301b-3p mature miRNA
• Sequence: 55 - CAGUGCAAUGGUAUUGUCAAAGC - 77
• Evidence: experimental ; miRAP-cloned [1], cloned [2], 454 [3], Illumina [4-5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 16973894
   Mouse microRNA profiles determined with a new and sensitive cloning method
   "Takada S, Berezikov E, Yamashita Y, Lagos-Quintana M, Kloosterman WP, Enomoto M, Hatanaka H, Fujiwara S, Watanabe H, Soda M, Choi YL, Plasterk RH, Cuppen E, Mano H"
   "Nucleic Acids Res (2006) 34:e115


5. PubMed ID: 17989215
   RNA sequence analysis defines Dicer's role in mouse embryonic stem cells
   "Calabrese JM, Seila AC, Yeo GW, Sharp PA"
   "Proc Natl Acad Sci U S A (2007) 104:18097-18102