Stem-loop mmu-mir-652

Accession

MI0004965

Symbol

MGI: Mir652

Description

Mus musculus mmu-mir-652 precursor miRNA mir-652

Gene
family

RF00872; mir-652

Literature search

12 open access papers mention mmu-mir-652
(22 sentences)

Sequence

78918 reads, 461 reads per million, 104 experiments

aggaacagcuauguacugcaCAACCCUAGGAGGGGGUGCCAUUCacauagaguauaauugAAUGGCGCCACUAGGGUUGUGcaguguacagccuacac
.......(((.((((((((((((((((((.....(((((((((((..((.....))..))))))))))).)))))))))))))))))).)))......

Structure

aggaaca   a                  GAGGG           ca  g 
       gcu uguacugcaCAACCCUAG     GGUGCCAUUCa  ua a
       ||| ||||||||||||||||||     |||||||||||  || g
       cga augugacGUGUUGGGAUC     CCGCGGUAAgu  au u
-cacauc   c                  ----A           ua  a 

Annotation confidence High

Comments

The predominant miRNA cloned by Langraf et al. has a 3' terminal U residue, which is incompatible with the genome sequence [2].

Genome context

chrX: 142739000-142739097 [+]

Mature mmu-miR-652-5p

• Accession: MIMAT0017260
• Description: Mus musculus mmu-miR-652-5p mature miRNA
• Sequence: 21 - CAACCCUAGGAGGGGGUGCCAUUC - 44
• Evidence: experimental ; 454 [4], Illumina [5]

Mature mmu-miR-652-3p

• Accession: MIMAT0003711
• Description: Mus musculus mmu-miR-652-3p mature miRNA
• Sequence: 61 - AAUGGCGCCACUAGGGUUGUG - 81
• Evidence: experimental ; cloned [2], Illumina [3,5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 20668074
   Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68
   "Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H"
   "J Virol (2010) 84:10266-10275


5. PubMed ID: 16566924
   Identification of new central nervous system specific mouse microRNAs
   "Wheeler G, Ntounia-Fousara S, Granda B, Rathjen T, Dalmay T"
   "FEBS Lett (2006) 580:2195-2200