Stem-loop mmu-mir-181d

Accession

MI0005450

Symbol

MGI: Mir181d

Description

Mus musculus mmu-mir-181d precursor miRNA

Literature search

123 open access papers mention mmu-mir-181d
(661 sentences)

Sequence

282980 reads, 636 reads per million, 107 experiments

acaauuAACAUUCAUUGUUGUCGGUGGGUugugaggaggcagccagaCCCACCGGGGGAUGAAUGUCAcugu
.......(((((((((....((((((((((....((......)).))))))))))..)))))))))......

Structure

acaauuA         GUUG          guga  ag 
       ACAUUCAUU    UCGGUGGGUu    gg  g
       |||||||||    ||||||||||    ||   
       UGUAAGUAG    GGCCACCCag    cc  c
-ugucAC         --GG          ---a  ga 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr8: 84178716-84178787 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-181d

Mature mmu-miR-181d-5p

• Accession: MIMAT0004324
• Description: Mus musculus mmu-miR-181d-5p mature miRNA
• Sequence: 7 - AACAUUCAUUGUUGUCGGUGGGU - 29
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

Mature mmu-miR-181d-3p

• Accession: MIMAT0017264
• Description: Mus musculus mmu-miR-181d-3p mature miRNA
• Sequence: 48 - CCCACCGGGGGAUGAAUGUCA - 68
• Evidence: experimental ; Illumina [4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009