Stem-loop bta-let-7b

Accession

MI0005453

Description

Bos taurus bta-let-7b precursor miRNA

Literature search

290 open access papers mention bta-let-7b
(1282 sentences)

Sequence

16374657 reads, 7846.0 reads per million, 321 experiments

cggggUGAGGUAGUAGGUUGUGUGGUUucaggguagugauguugcccccucggaagauaaCUAUACAACCUACUGCCUUCC
...((.(((((((((((((((((((((((.((((((.....))))))(....)..)).)))))))))))))))))))))))

Structure

cgg  U                     -  -------a      u 
   gg GAGGUAGUAGGUUGUGUGGUU uc        ggguag g
   || ||||||||||||||||||||| ||        |||||| a
   CC UUCCGUCAUCCAACAUAUCaa ag        cccguu u
---  -                     u  aaggcucc      g 

Annotation confidence High

Comments

The 3' end of the bovine let-7b hairpin precursor falls in a gap in the genome assembly. The sequence shown here is predicted from human.

Genome context

5: 116409210-116409290 [+]

Clustered miRNAs

3 other miRNAs are < 10 kb from bta-let-7b

Mature bta-let-7b-5p

• Accession: MIMAT0004331
• Description: Bos taurus bta-let-7b-5p mature miRNA
• Sequence: 6 - UGAGGUAGUAGGUUGUGUGGUU - 27
• Evidence: experimental ; cloned [1-2]

Mature bta-let-7b-3p

• Accession: MIMAT0060914
• Description: Bos taurus bta-let-7b-3p mature miRNA
• Sequence: 61 - CUAUACAACCUACUGCCUUCC - 81
• Evidence: experimental ; Illumina [1]

References

1. PubMed ID: 17306260
   Identification and characterization of microRNAs from the bovine adipose tissue and mammary gland
   "Gu Z, Eleswarapu S, Jiang H"
   "FEBS Lett (2007) 581:981-988


2. PubMed ID: 19758457
   Characterization of bovine miRNAs by sequencing and bioinformatics analysis
   Jin W, Grant JR, Stothard P, Moore SS, Guan LL
   BMC Mol Biol (2009) 10:90