Stem-loop hsa-mir-874

Accession

MI0005532

Symbol

HGNC: MIR874

Description

Homo sapiens hsa-mir-874 precursor miRNA mir-874

Gene
family

RF00919; mir-874

Literature search

23 open access papers mention hsa-mir-874
(223 sentences)

Sequence

34257 reads, 52 reads per million, 101 experiments

uuagcccugCGGCCCCACGCACCAGGGUAAGAgagacucucgcuucCUGCCCUGGCCCGAGGGACCGAcuggcugggc
((((((...(((.(((.((..((((((((((.(((...))).))...))))))))..)).))).)))...))))))..

Structure

--      cug   C   A  CA        ---  A   a 
  uuagcc   CGG CCC CG  CCAGGGUA   AG gag  
  ||||||   ||| ||| ||  ||||||||   || ||| c
  ggucgg   GCC GGG GC  GGUCCCGU   uc cuc  
cg      ucA   A   A  CC        Ccu  g   u 

Annotation confidence Medium

Genome context

chr5: 137647572-137647649 [-]

Disease association

hsa-mir-874 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-874-3p

• Accession: MIMAT0004911
• Description: Homo sapiens hsa-miR-874-3p mature miRNA
• Sequence: 47 - CUGCCCUGGCCCGAGGGACCGA - 68
• Evidence: experimental ; cloned [1-2], Illumina [3]

Mature hsa-miR-874-5p

• Accession: MIMAT0026718
• Description: Homo sapiens hsa-miR-874-5p mature miRNA
• Sequence: 10 - CGGCCCCACGCACCAGGGUAAGA - 32
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45