Stem-loop mmu-mir-466d

Accession

MI0005546

Symbol

MGI: Mir466d

Description

Mus musculus mmu-mir-466d precursor miRNA

Literature search

30 open access papers mention mmu-mir-466d
(97 sentences)

Sequence

17288 reads, 357 reads per million, 100 experiments

cauguguguuUGUGUGUGCGUACAUGUACAUGuguguauaugaauauacaUAUACAUACACGCACACAUAGauacgcacgcacacacacacacagg
..(((((((.(((((((((((((((((.(.((((((((((((......)))))))))))).)...)))).).)))))))))))).)))))))....

Structure

--ca       u            - -    --A A            aa 
    ugugugu UGUGUGUGCGUA C AUGU   C UGuguguauaug  u
    ||||||| |||||||||||| | ||||   | ||||||||||||   
    acacaca acacgcacgcau G UACA   G ACAUACAUAUac  a
ggac       c            a A    CAC C            au 

Annotation confidence High

Comments

miR-466d-3p reported in [1] has an additional 3' U base which is inconsistent with the current genome sequence (as shown here).

Genome context

chr2: 10511967-10512062 [+]

Clustered miRNAs

22 other miRNAs are < 10 kb from mmu-mir-466d

Mature mmu-miR-466d-5p

• Accession: MIMAT0004930
• Description: Mus musculus mmu-miR-466d-5p mature miRNA
• Sequence: 11 - UGUGUGUGCGUACAUGUACAUG - 32
• Evidence: experimental ; cloned [1], Illumina [3-4]

Mature mmu-miR-466d-3p

• Accession: MIMAT0004931
• Description: Mus musculus mmu-miR-466d-3p mature miRNA
• Sequence: 51 - UAUACAUACACGCACACAUAG - 71
• Evidence: experimental ; cloned [1], 454 [2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 17989215
   RNA sequence analysis defines Dicer's role in mouse embryonic stem cells
   "Calabrese JM, Seila AC, Yeo GW, Sharp PA"
   "Proc Natl Acad Sci U S A (2007) 104:18097-18102