Stem-loop ame-mir-190

Accession

MI0005750

Description

Apis mellifera ame-mir-190 precursor miRNA

Literature search

2 open access papers mention ame-mir-190
(4 sentences)

Sequence

caaacaagucgucugguuuccguaAGAUAUGUUUGAUAUUCUUGGUUGUUuuuuaaagaaucgaccaggaaucaaacauauuauuaugguggucagaaaa
...........(((((((.((((((((((((((((((..(((((((((.((((...)))).))))))))))))))))))))).)))))).)))))))...

Structure

caaacaagucg       u      -            AU         U    u 
           ucugguu ccguaA GAUAUGUUUGAU  UCUUGGUUG Uuuu  
           ||||||| |||||| ||||||||||||  ||||||||| |||| a
           agacugg gguauu uuauacaaacua  aggaccagc aaga  
--------aaa       u      a            --         u    a 

Annotation confidence Low

Comments

Weaver et al. identify this bee homolog of human mir-190b [1]. They also report a second predicted hairpin on the opposite strand, with RT-PCR evidence for the expression of a second mature miRNA (UAAUAAUAUGUUUGAUUCCUGG).

Genome context

CM000064.5: 9278012-9278111 [+]

Mature ame-miR-190-5p

• Accession: MIMAT0004440
• Description: Apis mellifera ame-miR-190-5p mature miRNA
• Sequence: 25 - AGAUAUGUUUGAUAUUCUUGGUUGUU - 50
• Evidence: experimental ; RTPCR [1], Illumina [2]

References

1. PubMed ID: 17543122
   Computational and transcriptional evidence for microRNAs in the honey bee genome
   Weaver DB, Anzola JM, Evans JD, Reid JG, Reese JT, Childs KL, Zdobnov EM, Samanta MP, Miller J, Elsik CG
   Genome Biol (2007) 8:R97


2. PubMed ID: 22409512
   Behavioral plasticity in honey bees is associated with differences in brain microRNA transcriptome
   "Greenberg JK, Xia J, Zhou X, Thatcher SR, Gu X, Ament SA, Newman TC, Green PJ, Zhang W, Robinson GE, Ben-Shahar Y"
   "Genes Brain Behav (2012) 11:660-670