Stem-loop mmu-mir-1b

Accession

MI0006283

Symbol

MGI: Mir1b

Description

Mus musculus mmu-mir-1b precursor miRNA

Literature search

283 open access papers mention mmu-mir-1b
(2867 sentences)

Sequence

20208831 reads, 21 reads per million, 99 experiments

uuccuuuagcuucuucuuggcggacauuaccuacccaaaaUACAUACUUCUUUACAUUCCAuagcacugaauguucauaUGGGUACAUAAAGAAGUAUGUGCucugaguaggcacuccugcg
...................((((......(((((.((...((((((((((((((...(((((((.((.....)).).))))))....))))))))))))))...)).))))).....)))).

Structure

uuccuuuagcuucuucuug    acauua     c  aaa              -CAU      - c  u 
                   gcgg      ccuac ca   UACAUACUUCUUUA    UCCAua g ac g
                   ||||      ||||| ||   ||||||||||||||    |||||| | || a
                   cguc      ggaug gu   GUGUAUGAAGAAAU    GGGUau c ug a
------------------g    -cucac     a  cuC              ACAU      a u  u 

Annotation confidence High

Comments

Calabrese et al. report the detection of mature products from the antisense strand of mouse mir-1-2, at lower abundance than sense miR-1 [1].

Genome context

chr18: 10785446-10785567 [+]

Clustered miRNAs

2 other miRNAs are < 10 kb from mmu-mir-1b

Mature mmu-miR-1b-5p

• Accession: MIMAT0005835
• Description: Mus musculus mmu-miR-1b-5p mature miRNA
• Sequence: 41 - UACAUACUUCUUUACAUUCCA - 61
• Evidence: experimental ; 454 [1], Illumina [2]

Mature mmu-miR-1b-3p

• Accession: MIMAT0017326
• Description: Mus musculus mmu-miR-1b-3p mature miRNA
• Sequence: 80 - UGGGUACAUAAAGAAGUAUGUGC - 102
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


2. PubMed ID: 17989215
   RNA sequence analysis defines Dicer's role in mouse embryonic stem cells
   "Calabrese JM, Seila AC, Yeo GW, Sharp PA"
   "Proc Natl Acad Sci U S A (2007) 104:18097-18102