Stem-loop hsa-mir-323b

Accession

MI0014206

Symbol

HGNC: MIR323B

Description

Homo sapiens hsa-mir-323b precursor miRNA

Literature search

47 open access papers mention hsa-mir-323b
(109 sentences)

Sequence

277 reads, 21 reads per million, 29 experiments

ugguacucggagggAGGUUGUCCGUGGUGAGUUCGCAuuauuuaaugaugCCCAAUACACGGUCGACCUCUUuucgguauca
((((((.(((((((((((((.(((((........(((((((...)))))))......))))).)))))))))))))))))))

Structure

      u             U     GUGAGUUC       u 
ugguac cggagggAGGUUG CCGUG        GCAuuau  
|||||| ||||||||||||| |||||        ||||||| u
acuaug gcuuUUCUCCAGC GGCAC        Cguagua  
      -             U     --AUAACC       a 

Annotation confidence High

Comments

miR-323b-5p was previously named miR-453 here and in [1,2], but appears to be processed from the same hairpin as miR-332b-3p identified in [3]. Entries for mir-323b and mir-453 are merged here.

Genome context

chr14: 101056219-101056300 [+]

Clustered miRNAs

18 other miRNAs are < 10 kb from hsa-mir-323b

Mature hsa-miR-323b-5p

• Accession: MIMAT0001630
• Description: Homo sapiens hsa-miR-323b-5p mature miRNA
• Sequence: 15 - AGGUUGUCCGUGGUGAGUUCGCA - 37
• Evidence: experimental ; cloned [1-2]

Mature hsa-miR-323b-3p

• Accession: MIMAT0015050
• Description: Homo sapiens hsa-miR-323b-3p mature miRNA
• Sequence: 51 - CCCAAUACACGGUCGACCUCUU - 72
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15891114
   Clustering and conservation patterns of human microRNAs
   "Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H"
   "Nucleic Acids Res (2005) 33:2697-2706


3. PubMed ID: 20300190
   Characterization of the Melanoma miRNAome by Deep Sequencing
   "Stark MS, Tyagi S, Nancarrow DJ, Boyle GM, Cook AL, Whiteman DC, Parsons PG, Schmidt C, Sturm RA, Hayward NK"
   "PLoS One (2010) 5:e9685