Stem-loop xtr-mir-449b

Accession

MI0018161

Description

Xenopus tropicalis xtr-mir-449b precursor miRNA

Literature search

1 open access papers mention xtr-mir-449b
(2 sentences)

Sequence

297 reads, 18.0 reads per million, 4 experiments

accugcuuuggguAGGCAGUGUAGUUUUAGCUGGCUGcuugcuauuaacuccagCAGUCGCUAAUACUCUGCCACcggcagcaggg
.((((((.(.(((.(((((.(((...(((((.(((((((.............))))))))))))))).)))))))).).)))))).

Structure

a      u g   A     U   GUU     U       ugcua 
 ccugcu u ggu GGCAG GUA   UUAGC GGCUGcu     u
 |||||| | ||| ||||| |||   ||||| |||||||     u
 ggacga g cCA CCGUC CAU   AAUCG CUGACga     a
g      c g   -     U   ---     -       ccuca 

Annotation confidence High

Comments

Expression of the miR-449 family sequences is validated in X. laevis by SOLID sequencing [1].

Genome context

1: 191769481-191769566 [+]

Clustered miRNAs

3 other miRNAs are < 10 kb from xtr-mir-449b

Mature xtr-miR-449b-5p

• Accession: MIMAT0022745
• Description: Xenopus tropicalis xtr-miR-449b-5p mature miRNA
• Sequence: 14 - AGGCAGUGUAGUUUUAGCUGGCUG - 37
• Evidence: not_experimental

Mature xtr-miR-449b-3p

• Accession: MIMAT0022746
• Description: Xenopus tropicalis xtr-miR-449b-3p mature miRNA
• Sequence: 55 - CAGUCGCUAAUACUCUGCCAC - 75
• Evidence: not_experimental

References

1. PubMed ID: 21602795
   Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway
   "Marcet B, Chevalier B, Luxardi G, Coraux C, Zaragosi LE, Cibois M, Robbe-Sermesant K, Jolly T, Cardinaud B, Moreilhon C, Giovannini-Chami L, Nawrocki-Raby B, Birembaut P, Waldmann R, Kodjabachian L, Barbry P"
   "Nat Cell Biol (2011) 13:693-699