miRBase entry: cel-mir-34

Stem-loop cel-mir-34


Accession
MI0000005
Description
Caenorhabditis elegans cel-mir-34 precursor miRNA mir-34
Gene
family?
RF00456; mir-34

Literature search
10 open access papers mention cel-mir-34
(28 sentences)

Sequence

782992 reads, 2563 reads per million, 16 experiments
cggacaaugcucgagAGGCAGUGUGGUUAGCUGGUUGcauauuuccuugacaACGGCUACCUUCACUGCCACCCcgaacaugucguccaucuuugaa
.((((.(((.(((.(.(((((((.((.((((((.(((((........)).))))))))).)).)))))))..).))).)))...)))).........

Structure
--------c    --a   c   a -A       U  U      G   -  uau 
         ggac   aug ucg g  GGCAGUG GG UAGCUG UUG ca   u
         ||||   ||| ||| |  ||||||| || |||||| ||| ||    
         ccug   uac agc C  CCGUCAC UC AUCGGC Aac gu   u
aaguuucua    cug   a   C CA       U  C      -   a  ucc 


Annotation confidence High
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Genome context
chrX: 2969752-2969848 [-]

Database links

Mature cel-miR-34-5p

Accession MIMAT0000005
Description Caenorhabditis elegans cel-miR-34-5p mature miRNA
Sequence 16 - AGGCAGUGUGGUUAGCUGGUUG - 37
Evidence experimental
cloned [1-3], Northern [1], PCR [4], 454 [5], Illumina [6], CLIPseq [7]
Database links
Predicted targets

Mature cel-miR-34-3p

Accession MIMAT0015093
Description Caenorhabditis elegans cel-miR-34-3p mature miRNA
Sequence 53 - ACGGCUACCUUCACUGCCACCC - 74
Evidence experimental
CLIPseq [7]
Database links

References

  1. PubMed ID: 11679671
    An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    "Lau NC, Lim LP, Weinstein EG, Bartel DP"
    "Science (2001) 294:858-862

  2. PubMed ID: 12672692
    The microRNAs of Caenorhabditis elegans
    "Lim LP, Lau NC, Weinstein EG, Abdelhakim A, Yekta S, Rhoades MW, Burge CB, Bartel DP"
    "Genes Dev (2003) 17:991-1008

  3. PubMed ID: 12747828
    MicroRNAs and other tiny endogenous RNAs in C. elegans
    "Ambros V, Lee RC, Lavanway A, Williams PT, Jewell D"
    "Curr Biol (2003) 13:807-818

  4. PubMed ID: 12769849
    Computational and experimental identification of C. elegans microRNAs
    "Grad Y, Aach J, Hayes GD, Reinhart BJ, Church GM, Ruvkun G, Kim J"
    "Mol Cell (2003) 11:1253-1263

  5. PubMed ID: 17174894
    Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    "Ruby JG, Jan C, Player C, Axtell MJ, Lee W, Nusbaum C, Ge H, Bartel DP"
    "Cell (2006) 127:1193-1207

  6. PubMed ID: 19460142
    Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
    Kato M, de Lencastre A, Pincus Z, Slack FJ
    Genome Biol (2009) 10:R54

  7. PubMed ID: 20062054
    Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
    "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
    "Nat Struct Mol Biol (2010) 17:173-179