miRBase entry: hsa-mir-93

Stem-loop hsa-mir-93

Homo sapiens hsa-mir-93 precursor miRNA
Gene family
MIPF0000001; mir-17

Caution, this is an AI generated summary based on literature. This may have errors. ?

MIR93 is a microRNA that exhibits upregulated expression levels despite having strongly hypermethylated promoters [PMC4198682]. In a study examining patients with MHT, MIR93, along with miR191, was analyzed using the logistic regression analysis forward method to determine if these parameters could predict abnormal CT findings [PMC7430915].

Literature search
297 open access papers mention hsa-mir-93
(1900 sentences)


429913 reads, 1906 reads per million, 154 experiments

          -CA       -     U    G   u  gau 
cugggggcuc   AAGUGCU GUUCG GCAG UAG gu   u
||||||||||   ||||||| ||||| |||| ||| ||   a
ggcccccgaG   UUCACGA CGAGU CGUC Auc ca   c
          CCC       U     -    -   -  acc 

Annotation confidence High
Do you think this miRNA is real?
Mourelatos et al. identified two copies of this sequence mapping to chromosome 7, and assigned the names mir-93-7.1 and mir-93-7.2 [1]. Subsequent genome assemblies suggest the presence of only one miR-93 locus on chromosome 7. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [5]. The 5' end of the miRNA may be offset with respect to previous annotations.

Genome context
chr7: 100093768-100093847 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from hsa-mir-93
Name Accession Chromosome Start End Strand Confidence

Disease association
hsa-mir-93 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID

Biological pathways
hsa-mir-93 is involved in one or more biological pathways:
(Source: Reactome)
Biological reactions
hsa-mir-93 is involved in one or more regulation/signalling events:
(Source: Reactome)

Database links

Mature hsa-miR-93-5p

Accession MIMAT0000093
Description Homo sapiens hsa-miR-93-5p mature miRNA
Evidence experimental
cloned [1,3-6], Northern [4]
Database links
Predicted targets

Mature hsa-miR-93-3p

Accession MIMAT0004509
Description Homo sapiens hsa-miR-93-3p mature miRNA
Evidence experimental
cloned [5]
Database links
Predicted targets


  1. PubMed ID: 12554860
    Numerous microRNPs in neuronal cells containing novel microRNAs
    "Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G"
    "RNA (2003) 9:180-186

  2. PubMed ID: 15325244
    Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells
    "Kasashima K, Nakamura Y, Kozu T"
    "Biochem Biophys Res Commun (2004) 322:403-410

  3. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  4. PubMed ID: 17616659
    Patterns of known and novel small RNAs in human cervical cancer
    "Lui WO, Pourmand N, Patterson BK, Fire A"
    "Cancer Res (2007) 67:6031-6043

  5. PubMed ID: 11914277
    miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
    "Mourelatos Z, Dostie J, Paushkin S, Sharma A, Charroux B, Abel L, Rappsilber J, Mann M, Dreyfuss G"
    "Genes Dev (2002) 16:720-728

  6. PubMed ID: 15978578
    Identification of human fetal liver miRNAs by a novel method
    "Fu H, Tie Y, Xu C, Zhang Z, Zhu J, Shi Y, Jiang H, Sun Z, Zheng X"
    "FEBS Lett (2005) 579:3849-3854